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- Table of Contents
TNFRSF11A Antibodies
AND TNFRSF11A ELISA kits, TNFRSF11A Proteins
Many biological assays use antibodies to detect TNFRSF11A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNFRSF11A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNFRSF11A antibodies...
Designing a Western blot for TNFRSF11A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TNFRSF11A Western Blot GuideTNFRSF11A Infographic by Boster Bio
All TNFRSF11A Products
Product
Figures
Specificity
Applications
Price
Human RANK ELISA Kit PicoKine®
1 Citations
Human
ELISA
$499
Cat # EK0829
96 wells/kit, with removable strips.
Cat # EK0829
96 wells/kit, with removable strips.
Mouse RANK / CD265 ELISA Kit PicoKine®
1 Citations
Mouse
ELISA
$499
Cat # EK0830
96 wells/kit, with removable strips.
Cat # EK0830
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # FEK0830
96 wells/kit, with removable strips.
Cat # FEK0830
96 wells/kit, with removable strips.
Anti-RANK/Tnfrsf11a Picoband® Antibody
1 Citations
Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01064-3
100 μg/vial
Cat # A01064-3
100 μg/vial
SDS-PAGE, Bioactivity
$293
Cat # PROTO35305
Starting from 10ug
Cat # PROTO35305
Starting from 10ug
TNFRSF11A Overview
Facts about Tumor necrosis factor receptor superfamily member 11A.
Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A)
Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis.
Involved in the regulation of interactions between T-cells and dendritic cells..
Gene Information
| Human | |
|---|---|
| Gene Name: | TNFRSF11A |
| Uniprot: | Q9Y6Q6 |
| Entrez: | 8792 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD265 antigen; CD265; FEO; loss of heterozygosity, 18, chromosomal region 1; ODFR; ODFROSTS; OFE; OPTB7; Osteoclast differentiation factor receptor; PDB2; RANK; RANKLOH18CR1; Receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; TNFRSF11A; TRANCE R; TRANCER; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily, member 11a, activator of NFKB; tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Molecular Weight
Mass (kDA):
66.034 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 18q21.33 |
| Sequence: | 18; NC_000018.10 (62325287..62391288) |
Tissue Specificity
Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland.
Subcellular Localizations
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform RANK-e5a]: Cell membrane; Single-pass type I membrane protein.
Diseases
- Osteoporosis
- Osteopenia
- Bone Diseases
- Arthritis
- Osteolysis
- Rheumatoid Arthritis
- Malignant Neoplasms
- Neoplasms
- Inflammation
- Neoplasm Metastasis
- Bone Neoplasms
- Multiple Myeloma
- Metastatic Malignant Neoplasm To The Bone
Interacting Proteins
- EGFR
- TNFSF11
- TRAF2
Pathways
- Bone Resorption
- Osteoclast Differentiation
- Bone Remodeling
- Pathogenesis
- Secretion
- Osteoclast Development
- Localization
- Cell Proliferation
- Osteoblast Differentiation
- Cell Differentiation
- Immune Response
- Cell Growth
- Cytokine Production
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Ubiquitination
- Dephosphorylation
- Glycosylation
Research Areas
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNFRSF11A
bosterbio.com/bosterbio-gene-info-cards/TNFRSF11A
References
PMID: 9367155 by Anderson D.M., et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.
PMID: 23664977 by Sirinian C., et al. Alternative splicing generates a truncated isoform of human TNFRSF11A (RANK) with an altered capacity to activate NF-kappaB.
6 Publications of Boster TNFRSF11A Antibodies & ELISA Kits
- PubMed ID: 10.1186/s13052-019-0748-1, OPG / RANK / RANKL signaling axis in patients with type I diabetes: Associations...
- PubMed ID: 10.1016/j.bioactmat.2021.05.003, Calcium phosphate-based materials regulate osteoclast-mediated osseointegration
- PubMed ID: 10.1002/bem.22059, Effect of intervention initiation timing of pulsed electromagnetic field on ovar...
- PubMed ID: 10.1002/bem.22059, Effect of intervention initiation timing of pulsed electromagnetic field on ovar...
- PubMed ID: 10.1002/bem.22059, Effect of intervention initiation timing of pulsed electromagnetic field on ovar...
- PubMed ID: -, Xiaogang Wang,Yuanman Yu,Luli Ji,Zhen Geng,Jing Wang,Changsheng Liu,Calcium phos...
*More publications can be found for each product on its corresponding product page