Product Info Summary
SKU: | M00004-3 |
---|---|
Size: | 100uL |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Beta-Catenin 1 (CTNNB1) Rabbit Monoclonal Antibody, Clone#RM276
View all beta-Catenin Antibodies
SKU/Catalog Number
M00004-3
Size
100uL
Form
Liquid
Description
Boster Bio Anti-Beta-Catenin 1 (CTNNB1) Rabbit Monoclonal Antibody, Clone#RM276 (Catalog # M00004-3). Tested in IHC, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Beta-Catenin 1 (CTNNB1) Rabbit Monoclonal Antibody, Clone#RM276 (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00004-3)
Host
Rabbit
Contents
50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Clonality
Monoclonal
Clone Number
RM276
Isotype
Rabbit IgG
Immunogen
A peptide corresponding to human Beta-Catenin.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody reacts to human Beta-Catenin (Catenin beta-1). This antibody may also react to mouse or rat Beta-Catenin, as predicted by immunogen homology.
Reactive Species
M00004-3 is reactive to CTNNB1 in Human
Applications
M00004-3 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
85.497kDa
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry (IHC): 1:500-1:1000 dilution
WB: 1:400-1:1000 dilution.
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western Blotting result
Western Blot of HeLa and 293 cells lysates using Anti--Catenin Rabbit Monoclonal Antibody (Clone RM276) at a 1:400 dilution.
Click image to see more details
Figure 2. IHC result
Immunohistochemical staining of formalin fixed and paraffin embedded human breast cancer tissue sections using Anti--Catenin Rabbit Monoclonal Antibody (Clone RM276) at a 1:1000 dilution.
Protein Target Info & Infographic
Gene/Protein Information For CTNNB1 (Source: Uniprot.org, NCBI)
Gene Name
CTNNB1
Full Name
Catenin beta-1
Weight
85.497kDa
Superfamily
beta-catenin family
Alternative Names
bCatenin; beta 1 (88kD); beta-Catenin; catenin (cadherin-associated protein), beta 1, 88kDa; catenin beta-1; CTNNB; CTNNB1; DKFZp686D02253; FLJ25606; FLJ37923 CTNNB1 CTNNB, EVR7, MRD19, NEDSDV, armadillo catenin beta 1 catenin beta-1|catenin (cadherin-associated protein), beta 1, 88kDa
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CTNNB1, check out the CTNNB1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CTNNB1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Beta-Catenin 1 (CTNNB1) Rabbit Monoclonal Antibody, Clone#RM276 (M00004-3)
Hello CJ!
M00004-3 has been cited in 5 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Piao HY,Guo S,Wang Y,Zhang J.Exosome-transmitted lncRNA PCGEM1 promotes invasive and metastasis in gastric cancer by maintaining the stability of SNAI1.Clin Transl Oncol.2020 Jun 9.doi:10.1007/s12094-020-02412-9.Epub ahead of print.PMID:32519176.
Species: Human
M00004-3 usage in article: APP:WB, SAMPLE:AGS CELL AND MKN45 CELL, DILUTION:1:200
Dark Aberrant Crypt Foci with activated Wnt pathway are related to tumorigenesis in the colon of AOM-treated rat
Anti-cancer drug 3, 3%u2032-diindolylmethane activates Wnt4 signaling to enhance gastric cancer cell stemness and tumorigenesis
Li C, Liu J, Zhang Q, Cui K, Ge Q, Wang C, Chen Z. Int J Oncol. 2018 Jun;52(6):1815-1826. doi: 10.3892/ijo.2018.4346. Epub 2018 Mar 29. Upregulation of E-cadherin expression mediated by a novel dsRNA suppresses the growth and metastasis of bladder...
Zhang JH, Jiao LY, Li TJ, Zhu YY, Zhou JW, Tian J. J Cancer. 2017 Jun 3;8(9):1598-1608. doi: 10.7150/jca.18744. eCollection 2017. GSK-3β suppresses HCC cell dissociation in vitro by upregulating epithelial junction proteins and inhibiting Wnt/β-ca...
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