AGER Antibodies

AND AGER ELISA kits, AGER Proteins

Many biological assays use antibodies to detect AGER, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AGER in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AGER antibodies...

We validate the specificity of these antibodies to AGER by testing them on tissues known to express AGER positively and negatively. Browse below to find the AGER antibody that suites your experiment. We have 15 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for AGER? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the AGER Western Blot Guide

AGER Infographic by Boster Bio

All AGER Products

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Product

Figures

Specificity

Applications

Price

Anti-RAGE/AGER Antibody Picoband®

6 Citations

Western blot analysis of RAGE/AGER using anti-RAGE/AGER antibody (A03438-1)

IHC analysis of RAGE/AGER using anti-RAGE/AGER antibody (A03438-1)

IF analysis of RAGE/AGER using anti-RAGE/AGER antibody (A03438-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03438-1
100 μg/vial

Human RAGE PicoKine® Quick ELISA Kit

Human

ELISA

$499
Cat # FEK0827
96 wells/kit, with removable strips.

Anti-RAGE/AGER Antibody Picoband® (monoclonal, 5C6C1)

Western blot analysis of RAGE/AGER using anti-RAGE/AGER antibody (M03438-2)

IHC analysis of RAGE/AGER using anti-RAGE/AGER antibody (M03438-2)

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # M03438-2
100 μg/vial

Human Rage ELISA Kit PicoKine®

6 Citations

Human

ELISA

$499
Cat # EK0827
96 wells/kit, with removable strips.

Anti-Ager Antibody Picoband®

Western blot analysis of Ager using anti-Ager antibody (A03438-2)

Mouse, Rat

ELISA, WB

$370
Cat # A03438-2
100 µg/vial

Rat RAGE ELISA Kit PicoKine®

5 Citations

Rat RAGE PicoKine ELISA Kit standard curve

Rat

ELISA

$499
Cat # EK0971
96 wells/kit, with removable strips.

Mouse RAGE ELISA Kit PicoKine®

2 Citations

Mouse

ELISA

$499
Cat # EK0828
96 wells/kit, with removable strips.

Anti-RAGE/AGER Antibody Picoband®

2 Citations

Anti-RAGE antibody, PA1069, IHC(P)IHC(P): Rat Lung Tissue

Western blot analysis of RAGE using anti-RAGE antibody (PA1069)

Human, Mouse, Rat

IHC, IHC-F, WB

$370
Cat # PA1069
100 μg/vial

Anti-RAGE/AGER Antibody Picoband®

1 Citations

IHC analysis of RAGE using anti-RAGE antibody (PB9469)

Human, Mouse, Rat

IHC, WB

$370
Cat # PB9469
100 μg/vial

Anti-RAGE Rabbit Monoclonal Antibody

4 Citations

Western blot analysis of RAGE expression in mouse lung lysate

Western blotting results of RAGE in osteoblasts (n = 3)

Human, Mouse, Rat

$370
Cat # M03438
100 μl

Anti-AGER / RAGE Reference Antibody (XT-M4)

The purity of Anti-AGER/RAGE Reference Antibody (XT-M4)is more than 95%

Human, Mouse

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M03438-3
100 μg

RAGE (AGER) (NM_001136) Human Over-expression Lysate

RAGE (AGER) Human Over-expression Lysates NM_001136

Human

$628
Cat # LS000177
20 µg, 100 µg

Anti-RAGE AGER Antibody

1 Citations

Western blot analysis of RAGE on mouse lung lysates using anti-RAGE antibody at 1/1,000 dilution

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$405
Cat # A03438
100ul

Human RAGE Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

Human HMGB1 is coated at 20 ug/ml (100 ul/well) can bind Human RAGE

SDS-PAGE, Bioactivity

$281
Cat # PROTQ15109
Starting from 10ug

Human recombinant RAGE (Receptor for advanced glycation endproducts) protein, AF

Human

Cell Culture

$77
Cat # PROTQ15109-2
5ug,20ug,100ug

AGER Overview

Facts about Advanced glycosylation end product-specific receptor.

AGER 3D structure. Source: alphafold

Advanced glycosylation end product-specific receptor (AGER)

Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins that accumulate in vascular tissue in aging and at an accelerated rate in diabetes.

Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and specifically as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF- alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes.

Gene Information

Human
Gene Name:	AGER
Uniprot:	Q15109
Entrez:	177

Family

Belongs to:

No superfamily

Alternative Names

advanced glycosylation end product-specific receptor; AGER; RAGE isoform delta; RAGE isoform sRAGE-delta; RAGE; Receptor for advanced glycosylation end products; receptor for advanced glycosylation end-products; SCARJ1

Molecular Weight

Mass (kDA):
42.803 kDA

Genomic Context


Human

Location:	6p21.32
Sequence:	6; NC_000006.12 (32180968..32184380, complement)

Tissue Specificity

Endothelial cells.

Subcellular Localizations

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 10]: Cell membrane; Single-pass type I membrane protein.

Diseases

Diabetes Mellitus
Diabetic Nephropathy
Diabetes Mellitus, Non-insulin-dependent
Kidney Diseases
Inflammation
Malignant Neoplasms
Atherosclerosis
Lung Diseases
Fibrosis
Chronic Obstructive Airway Disease
Lung Diseases, Obstructive
Dysequilibrium Syndrome
Malignant Neoplasm Of Pancreas

Infective Disorder
Hypertensive Disease
Vascular Diseases
Alzheimer's Disease
Coronary Artery Disease
Pancreatic Neoplasm
Autoimmune Reaction

Interacting Proteins

DIAPH1
EGFR
Egfr
GRB2
HMGB1

MAPKAPK5
NCK1
PRKCZ
RHOA
S100B

S100P
TIRAP
TTR

Pathways

Pathogenesis
Glycosylation
Localization
Secretion
Transport
Cell Proliferation
Cell Killing
Insulin Secretion
Immune Response
Autolysis
Methylation

Neuroprotection
Gene Conversion
Cellular Localization
Metabolic Process
Tear Secretion
Autophagy

PTMs

Glycosylation
Phosphorylation

Biotinylation
Acetylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AGER

References

PMID: 1378843 by Neeper M., et al. Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins.

PMID: 7835890 by Sugaya K., et al. Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3.

20 Publications of Boster AGER Antibodies & ELISA Kits

PubMed ID: 10.1186/s12933-020-01068-7, Accumulation of advanced glycation end products (AGEs) is associated with the se...
PubMed ID: 10.1159/000448141, Accumulation of Advanced Glycation End Products Involved in Inflammation and Con...
PubMed ID: 10.1016/j.jep.2013.11.015, The anti-inflammation effect of Moutan Cortex on advanced glycation end products...
PubMed ID: 10.1016/j.etap.2020.103577, Protocatechuic acid improves hepatic insulin resistance and restores vascular ox...
PubMed ID: 10.1016/j.clnu.2021.02.040, Long lasting protective effects of early l-arginine treatment on endothelium in ...
PubMed ID: 10.1007/s00210-018-1583-4, Cinnamaldehyde ameliorates STZ-induced rat diabetes through modulation of IRS1/P...
PubMed ID: -, Rui Liu,Ying Shu,Wenhui Qi,Weili Rao,Zihan Fu,Zhenxiao Shi,Zhisheng Zhang,"Prote...
PubMed ID: 33581205, Lian Y,Zhu M,Chen J,Yang B,Lv Q,Wang L,Guo S,Tan X,Li C,Bu W,Ding W,Jia X,Feng L...
PubMed ID: -, Yudi Zhang,Chunhe Tao,Donglin Du, et al.Astragaloside IV Protects Against Diabet...
PubMed ID: 33294466, Liang Q,Lin Q,Li Y,Luo W,Huang X,Jiang Y,Qin C,Nong J,Chen X,Sooranna SR,Pinhu L...
PubMed ID: 18246495 , Radon-induced proteomic profile of lung tissue in rats
PubMed ID: 27026909, Ethyl pyruvate attenuated coxsackievirus B3-induced acute viral myocarditis by s...
PubMed ID: 28223765, Li JY, Lu YH, Zhang LW, Zhou PM, Chen T. Ann Dermatol. 2017 Feb;29(1):121-123. d...
PubMed ID: 28486941, Wang F, He Q, Wang J, Yuan Q, Guo H, Chai L, Wang S, Hu L, Zhang Y. BMC Compleme...
PubMed ID: 23442498, Qin Q, Niu J, Wang Z, Xu W, Qiao Z, Gu Y. Cardiovasc Diabetol. 2013 Feb 26;12:37...
PubMed ID: 23875897, Liu J, Wang S, Feng L, Ma D, Fu Q, Song Y, Jia X, Ma S. J Med Food. 2013 Jul;16(...
PubMed ID: 20100543, Wang L, Zhang X, Liu L, Yang R, Cui L, Li M. Neurosci Lett. 2010 Mar 8;471(3):15...
PubMed ID: 20043889, Wang L, Zhang X, Liu L, Cui L, Yang R, Li M, Du W. Brain Res. 2010 Mar 19;1321:1...
PubMed ID: 25279006, Xu L, Zang P, Feng B, Qian Q. Diabetol Metab Syndr. 2014 Sep 23;6(1):102. Doi: 1...
PubMed ID: 23219582, Feng L, Zhu M, Zhang M, Jia X, Cheng X, Ding S, Zhu Q. Int Immunopharmacol. 2013...

*More publications can be found for each product on its corresponding product page