- Table of Content
Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and specifically as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF- alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes.
|Sequence:||6; NC_000006.12 (32180968..32184380, complement)|
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 10]: Cell membrane; Single-pass type I membrane protein.
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