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- Table of Contents
Beta-2-microglobulin Antibodies
AND B2M ELISA kits, Beta-2-microglobulin Proteins
Many biological assays use antibodies to detect Beta-2-microglobulin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Beta-2-microglobulin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Beta-2-microglobulin antibodies...
Designing a Western blot for Beta-2-microglobulin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the B2M Western Blot GuideB2M Infographic by Boster Bio
All B2M Products
Product
Figures
Specificity
Applications
Price
Anti-BCRP/ABCG2 Antibody Picoband®
6 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00457-2
100 μg/vial
Cat # A00457-2
100 μg/vial
Human
ELISA
$500
Cat # EZ1691
For 5 plates, 96 wells each
Cat # EZ1691
For 5 plates, 96 wells each
Human
ELISA
$499
Cat # EK1691
96 wells/kit, with removable strips.
Cat # EK1691
96 wells/kit, with removable strips.
Human
Flow Cytometry, IF, IHC, ICC, WB, ELISA (Cap)
$370
Cat # A00456-1
100 μg/vial
Cat # A00456-1
100 μg/vial
Human, Monkey
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00456-2
100 μg/vial
Cat # M00456-2
100 μg/vial
Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00456-2
100 μg/vial
Cat # A00456-2
100 μg/vial
Human, Mouse, Rat
IP, IF, ICC, WB
$370
Cat # M00456-1
100 μl
Cat # M00456-1
100 μl
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M09198-3
100 μg
Cat # M09198-3
100 μg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M09198-2
100 μg
Cat # M09198-2
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M09198-1
100 μg
Cat # M09198-1
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M09198
100 μg
Cat # M09198
100 μg
Human
$628
Cat # LS000567
20 µg, 100 µg
Cat # LS000567
20 µg, 100 µg
B2M Overview
Facts about Beta-2-microglobulin.
Beta-2-microglobulin (B2M)
Part of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and reduces its export to the cell surface (total protein levels do not change), likely resulting in defects in class I antigen presentation (PubMed:25356553).
Gene Information
| Human | |
|---|---|
| Gene Name: | B2M |
| Uniprot: | P61769 |
| Entrez: | 567 |
Family
| Belongs to: |
|---|
| beta-2-microglobulin family |
Alternative Names
B2M; beta 2Microglobulin; beta 2-Microglobulin; beta chain of MHC class I molecules; beta-2-microglobin; beta-2-microglobulin
Molecular Weight
Mass (kDA):
13.715 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q21.1 |
| Sequence: | 15; NC_000015.10 (44711492..44718877) |
Subcellular Localizations
Secreted. Cell surface. Detected in serum and urine (PubMed:1336137, PubMed:7554280).; (Microbial infection) In the presence of M.tuberculosis EsxA-EsxB complex decreased amounts of B2M are found on the cell surface (PubMed:25356553).
Diseases
- Malignant Neoplasms
- Neoplasms
- Multiple Myeloma
- Leukemia
- Kidney Diseases
- Malignant Paraganglionic Neoplasm
- Lymphoma
- Carcinoma
- Inflammation
- Kidney Failure, Chronic
- Hiv Infections
- Diabetes Mellitus
- Immunologic Deficiency Syndromes
Interacting Proteins
- CD1A
- CD1B
- CD244
- HFE
- HLA-A
- PCNA
Pathways
- Excretion
- Reverse Transcription
- Pathogenesis
- Glomerular Filtration
- Immune Response
- Secretion
- Cell Differentiation
- Transport
- Inflammatory Response
- Localization
- Methylation
- Cell Proliferation
- Aging
PTMs
- Methylation
- Acetylation
Research Areas
- Adaptive Immunity
- Cancer
- Diabetes Research
- Immunology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/B2M
bosterbio.com/bosterbio-gene-info-cards/B2M
References
PMID: 3312414 by Guessow D., et al. The human beta 2-microglobulin gene. Primary structure and definition of the transcriptional unit.
PMID: 16108498 by He X.H., et al. Cloning of human beta-microglobulin gene and its high expression in Escherichia coli.
3 Publications of Boster Beta-2-microglobulin Antibodies & ELISA Kits
- PubMed ID: 10.3892/ijo.2014.2448, β-elemene inhibits stemness, promotes differentiation and impairs chemoresistan...
- PubMed ID: 10.1016/j.jep.2013.10.028, The mechanism of the opening of the blood–brain barrier by borneol: A pharmaco...
- PubMed ID: -, Panchamia, Shail. (2020). To Investigate The Impact Of Gut Bacteria On Efflux Tr...
*More publications can be found for each product on its corresponding product page