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- Table of Contents
Collagen alpha-1(I) chain Antibodies
AND COL1A1 ELISA kits, Collagen alpha-1(I) chain Proteins
Many biological assays use antibodies to detect Collagen alpha-1(I) chain, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Collagen alpha-1(I) chain in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Collagen alpha-1(I) chain antibodies...
Designing a Western blot for Collagen alpha-1(I) chain? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the COL1A1 Western Blot GuideCOL1A1 Video by Boster Bio
All COL1A1 Products
Product
Figures
Specificity
Applications
Price
Anti-Collagen I/COL1A1 Antibody Picoband®
39 Citations
Human, Mouse
IHC, WB
$370
Cat # PA2140-1
100 μg/vial
Cat # PA2140-1
100 μg/vial
Anti-Collagen I/COL1A1 Antibody Picoband®
152 Citations
Mouse, Rat
IHC, WB
$370
Cat # PB9939
100 μg/vial
Cat # PB9939
100 μg/vial
Anti-Collagen I/COL1A1 Antibody Picoband®
39 Citations
Human
IF, IHC, WB
$370
Cat # PB9938
100 μg/vial
Cat # PB9938
100 μg/vial
Anti-Collagen I/COL1A1 Antibody Picoband®
14 Citations
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # PA2140-2
100 μg/vial
Cat # PA2140-2
100 μg/vial
Human Pro-collagen Iα1/COL1A1 ELISA Kit PicoKine®
11 Citations
Human
ELISA
$450
Cat # EK1692
96 wells/kit, with removable strips.
Cat # EK1692
96 wells/kit, with removable strips.
Human
IHC, WB
$370
Cat # M00624
100 μl
Cat # M00624
100 μl
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IHC, WB
$670
Cat # B00329
100ug
Cat # B00329
100ug
Anti-Collagen I COL1A1 Monoclonal Antibody
1 Citations
Human, Mouse, Rat
IF, IHC
$380
Cat # M00329-1
100ul
Cat # M00329-1
100ul
COL1A1 Overview
Facts about Collagen alpha-1(I) chain.
Collagen alpha-1(I) chain (COL1A1)
Type I collagen is a member of group I collagen (fibrillar forming collagen). .
Gene Information
| Human | |
|---|---|
| Gene Name: | COL1A1 |
| Uniprot: | P02452 |
| Entrez: | 1277 |
Family
| Belongs to: |
|---|
| fibrillar collagen family |
Alternative Names
Alpha-1 type I collagen; COL1A1; Collagen 1 alpha 1; Collagen 1; collagen alpha 1 chain type I; collagen alpha-1(I) chain; Collagen I alpha 1; collagen of skin, tendon and bone, alpha-1 chain; collagen, type I, alpha 1; Collagen1; Collagen-1; OI4; pro-alpha-1 collagen type 1
Molecular Weight
Mass (kDA):
138.941 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q21.33 |
| Sequence: | 17; NC_000017.11 (50184096..50201649, complement) |
Tissue Specificity
Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.
Subcellular Localizations
Secreted, extracellular space, extracellular matrix.
Diseases
- Osteogenesis Imperfecta
- Fibrosis
- Fracture
- Neoplasms
- Osteoporosis
- Dermatofibrosarcoma
- Dermatofibrosarcoma Protuberans
- Skin Neoplasms
- Osteopenia
- Malignant Neoplasms
- Connective Tissue Diseases
- Hypertrophy
- Inflammation
Interacting Proteins
- FN1
Pathways
- Pathogenesis
- Osteoblast Differentiation
- Cell Proliferation
- Secretion
- Regeneration
- Wound Healing
- Dentinogenesis
- Cell Growth
- Aging
- Ossification
- Translation
- Bone Resorption
- Reverse Transcription
PTMs
- Cleavage
- Phosphorylation
- Methylation
- Hydroxylation
- Demethylation
- Phosphorothioation
- Sulphation
- Carboxylation
Research Areas
- Cell Biology
- Cellular Markers
- Extracellular Matrix
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COL1A1
bosterbio.com/bosterbio-gene-info-cards/COL1A1
References
PMID: 2843432 by D'Alessio M., et al. Complete nucleotide sequence of the region encompassing the first twenty-five exons of the human pro alpha 1(I) collagen gene (COL1A1).
PMID: 3178743 by Tromp G., et al. Structure of a full-length cDNA clone for the prepro alpha 1(I) chain of human type I procollagen.
121 Publications of Boster Collagen alpha-1(I) chain Antibodies & ELISA Kits
- PubMed ID: 10.3136/fstr.15.249, Protective Effect of Cartilage-selenium Polysaccharide on Diethylnitrosamine-Ind...
- PubMed ID: 10.1186/s13395-018-0180-z, Myostatin and activin blockade by engineered follistatin results in hypertrophy ...
- PubMed ID: 10.1111/php.13156, Protective Effects of Ginseng Proteins on Photoaging of Mouse Fibroblasts Induce...
- PubMed ID: 10.1038/s41598-020-67514-4, Investigating the antifibrotic effect of the antiparasitic drug Praziquantel in ...
- PubMed ID: 10.1021/acsami.9b14800, Surface Epitaxial Crystallization-Directed Nanotopography for Accelerating Preos...
- PubMed ID: 10.1016/j.tiv.2017.10.008, The excitotoxity of NMDA receptor NR2D subtype mediates human fetal lung fibrobl...
- PubMed ID: 10.1016/j.jbc.2021.101479, Heparan sulfate is necessary for the early formation of nascent fibronectin and ...
- PubMed ID: 10.1016/j.ejogrb.2020.01.027, Low expression of collagen type-1 in sacrouterine ligament as risk factor of sta...
- PubMed ID: 10.1002/jat.3842, Food‐grade titanium dioxide (E171) by solid or liquid matrix administration in...
- PubMed ID: 10.1002/cbf.3457, Uncarboxylated osteocalcin promotes osteogenic differentiation of mouse bone mar...
- PubMed ID: 30888602, Wei X,Bao Y,Zhan X,Zhang L,Hao G,Zhou J,Chen Q.MiR-200a ameliorates peritoneal f...
- PubMed ID: 31169440, Li X,Bu X,Yan F,Wang F,Wei D,Yuan J,Zheng W,Su J,Yuan J.Deletion of discoidin do...
- PubMed ID: 31505422, Ge Y,Cheng R,Sun S,Zhang S,Li L,Jiang J,Yang C,Xuan X,Chen J.Fangxiao Formula al...
- PubMed ID: 33992834, Feng Y,Dong H,Sun B,Hu Y,Yang Y,Jia Y,Jia L,Zhong X,Zhao R.METTL3/METTL14 transa...
- PubMed ID: -, Yu WY,Cai W,Ying HZ, Zhang WY,Zhang HH,Yu CH.Exogenous Plant gma-miR-159a, Ident...
- PubMed ID: -, Jennifer Bosco,Zhiwei Zhou,Sofie Gabriëls,Mayank Verma,Nan Liu,Brian K. Miller,...
- PubMed ID: 33711827, Jiang Y,Liu JM,Huang JP,Lu KX,Sun WL,Tan JY,Li BX,Chen LL,Wu Y. Regeneration pot...
- PubMed ID: -, Lombardi, F.; Augello, F.R.; Palumbo, P.; Mollsi, E.; Giuliani, M.; Cimini, A.M....
- PubMed ID: 33721755, Zhou J,Li R,Liu Q,Zhang J,Huang H,Huang C,Zhang G,Zhao Y,Wu T,Tang Q,Huang Y,Zha...
- PubMed ID: -, Lan Chen,Xiaofang Ji,Manni Wang et al.Involvement of TLR4 Signaling Regulated-CO...
- PubMed ID: 33450323, Ma XL,Ding Y,Wu LM,Wang YX,Yao Y,Wang YX,Zhang YG,Niu JQ,He XX,Wang YQ.The gluca...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page