Anti-Collagen I/COL1A1 Antibody Picoband™

Boster Bio Anti-Collagen I/COL1A1 Antibody Picoband™ catalog # PB9938. Tested in IHC, WB applications. This antibody reacts with Human. Cited in 50 publication(s).

Product Info Summary

SKU: PB9938
Size: 100μg/vial
Reactive Species: Human
Host: Rabbit
Application: IHC, WB

Product Name

Anti-Collagen I/COL1A1 Antibody Picoband™

See all COL1A1 products

SKU/Catalog Number







Boster Bio Anti-Collagen I/COL1A1 Antibody Picoband™ catalog # PB9938. Tested in IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Collagen I/COL1A1 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9938)




Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.




A synthetic peptide corresponding to a sequence at the C-terminus of human Collagen I (1194-1218aa AGFDFSFLPQPPQEKAHDGGRYYRA), different from the related mouse and rat sequences by four amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

PB9938 is reactive to COL1A1 in Human


PB9938 is guaranteed for IHC, WB Boster Guarantee

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For COL1A1 (Source: Uniprot.Org, NCBI)

Uniprot ID


Gene ID


Gene Name


Full Name

Collagen alpha-1(I) chain




fibrillar collagen family

Alternative Names

Alpha-1 type I collagen; COL1A1; Collagen 1 alpha 1; Collagen 1; collagen alpha 1 chain type I; collagen alpha-1(I) chain; Collagen I alpha 1; collagen of skin, tendon and bone, alpha-1 chain; collagen, type I, alpha 1; Collagen1; Collagen-1; OI4; pro-alpha-1 collagen type 1 COL1A1 CAFYD, EDSARTH1, EDSC, OI1, OI2, OI3, OI4 collagen type I alpha 1 chain collagen alpha-1(I) chain|alpha-1 type I collagen|alpha1(I) procollagen|collagen alpha 1 chain type I|collagen alpha-1(I) chain preproprotein|collagen of skin, tendon and bone, alpha-1 chain|collagen, type I, alpha 1|pro-alpha-1 collagen type 1|type I proalpha 1|type I procollagen alpha 1 chain

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on COL1A1, check out the COL1A1 Infographic

COL1A1 infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for COL1A1: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

PB9938 has been cited in 50 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Jiang Y,Liu JM,Huang JP,Lu KX,Sun WL,Tan JY,Li BX,Chen LL,Wu Y. Regeneration potential of decellularized periodontal ligament cell sheets combined with 15-Deoxy-Δ12,14-prostaglandin J2nanoparticles in a rat periodontal defect. Biomed Mater.2021 Mar 12.doi:10.1088/1748-605X/abee61.Epub ahead of print.PMID:33711827.
Species: Human,Rat
PB9938 usage in article: APP:IHC, SAMPLE:MANDIBLES, DILUTION:1:100

Lombardi, F.; Augello, F.R.; Palumbo, P.; Mollsi, E.; Giuliani, M.; Cimini, A.M.; Cifone, M.G.; Cinque, B. Soluble Fraction from Lysate of a High Concentration Multi-Strain Probiotic Formulation Inhibits TGF-β1-Induced Intestinal Fibrosis on CCD-18Co Cells. Nutrients 2021,13,882.
Species: Human

Xu L,Sun N,Li G,Liu L.LncRNA H19 promotes keloid formation through targeting the miR-769-5p/EIF3A pathway.Mol Cell Biochem.2021 Jan 3.doi:10.1007/s11010-020-04024-x.Epub ahead of print.PMID:33389493.
Species: Human

Xu T,Pan L,Li L,Hu S,Zhou H,Yang C,Yang J,Li H,Liu Y,Meng X,Li J.MicroRNA-708 modulates Hepatic Stellate Cells activation and enhances extracellular matrix accumulation via direct targeting TMEM88. J Cell Mol Med. 2020 Jul;24(13):7127-7140.doi: 10.1111/jc
Species: Human
PB9938 usage in article: APP:IHC, SAMPLE:LIVER TISSUE, DILUTION:1:100

Ketamine analog methoxetamine induced inflammation and dysfunction of bladder in rats

Uncarboxylated osteocalcin inhibits high glucose-induced ROS production and stimulates osteoblastic differentiation by preventing the activation of PI3K/Akt %u2026

Synthesis, Biological Evaluation, and Docking Studies of a Novel Sulfonamido-Based Gallate as Pro-Chondrogenic Agent for the Treatment of Cartilage

Telmisartan improves vascular remodeling through ameliorating prooxidant and profibrotic mechanisms in hypertension via the involvement of transforming growth factor-?1

Induced pluripotent stem cell-conditioned medium suppresses pulmonary fibroblast-to-myofibroblast differentiation via the inhibition of TGF-?1/Smad pathway

Hydroxysafflor Yellow A Ameliorates Renal Fibrosis by Suppressing TGF-?1-Induced Epithelial-to-Mesenchymal Transition

An essential role for Wnt/?-catenin signaling in mediating hypertensive heart disease

Nano-hydroxyapatite/collagen film as a favorable substrate to maintain the phenotype and promote the growth of chondrocytes cultured in vitro

Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction

FOXA2 alleviates CCl4-induced liver fibrosis by protecting hepatocytes in mice

Lipoxin A4 improves erectile dysfunction in rats with type I diabetes by inhibiting oxidative stress and corporal fibrosis

Screening in larval zebrafish reveals tissue-specific distribution of fifteen fluorescent compounds

Long-term intravenous administration of carboxylated single-walled carbon nanotubes induces persistent accumulation in the lungs and pulmonary fibrosis via the nuclear factor-kappa B pathway.

Inhibitory effects of dimethyl ?-ketoglutarate in hepatic stellate cell activation

Role of transforming growth factor ?-1 in the pathogenesis of pelvic organ prolapse: A potential therapeutic target

Dietary Flavonoid Hyperoside Induces Apoptosis of Activated Human LX-2 Hepatic Stellate Cell by Suppressing Canonical NF-?B Signaling

Effects of rhBNP on myocardial fibrosis after myocardial infarction in rats

Protective effects of thalidomide on pulmonary injuries in a rat model of paraquat intoxication

Continuing Treatment with Salvia miltiorrhiza Injection Attenuates Myocardial Fibrosis in Chronic Iron-Overloaded Mice

Effects of Negative Pressure Wound Therapy on Mesenchymal Stem Cells Proliferation and Osteogenic Differentiation in a Fibrin Matrix

The Osteogenic Potential of Mesoporous Bioglasses/Silk and Non-Mesoporous Bioglasses/Silk Scaffolds in Ovariectomized Rats: In vitro and In vivo Evaluation

Effects of angiotensin II receptor antagonist, Losartan on the apoptosis, proliferation and migration of the human pancreatic stellate cells

Effects of pentoxifylline on the hepatic content of TGF-?1 and collagen in Schistosomiasis japonica mice with liver fibrosis

Estrogen reduces CCL4- induced liver fibrosis in rats

Hesperetin alleviates renal interstitial fibrosis by inhibiting tubular epithelial-mesenchymal transition in vivo and in vitro

Angiotensin II induces connective tissue growth factor expression in human hepatic stellate cells by a transforming growth factor ?-independent mechanism

Protective effects of baicalin on rabbit articular chondrocytes in vitro

The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-?1 pathway

Silver nanoparticles/chitosan oligosaccharide/poly(vinyl alcohol) nanofiber promotes wound healing by activating TGF?1/Smad signaling pathway

Uighur medicine abnormal savda munzip (ASMq) suppresses expression of collagen and TGF-?1 with concomitant induce Smad7 in human hypertrophic scar fibroblasts

Silica promotes the transdifferentiation of rat circulating fibrocytes in vitro

Andrographolide Enhances Proliferation and Prevents Dedifferentiation of Rabbit Articular Chondrocytes: An?In Vitro?Study

Effect of anterior cervical discectomy and fusion on adjacent segments in rabbits

Localization of Human Mesenchymal Stem Cells from Umbilical Cord Blood and Their Role in Repair of Diabetic Foot Ulcers in Rats

Luo L, Li J, Liu H, Jian X, Zou Q, Zhao Q, Le Q, Chen H0, Gao X, He C. Int J Mol Sci. 2017 May 12;18(5). pii: E1044. doi: 10.3390/ijms18051044. Adiponectin Is Involved in Connective Tissue Growth Factor-Induced Proliferation, Migration and Overpro...

Cheng L, Ge M, Lan Z, Ma Z, Chi W, Kuang W, Sun K, Zhao X, Liu Y, Feng Y, Huang Y, Luo M, Li L, Zhang B, Hu X, Xu L, Liu X, Huo Y, Deng H, Yang J, Xi Q, Zhang Y, Siegenthaler JA, Chen L. Arch Toxicol. 2018 Jan;92(1):469-485. doi: 10.1007/s00204-01...

Huang L, Jin P, Lin X, Lin C, Zheng L, Zhao J. Mol Med Rep. 2017 Mar;15(3):1149-1156. doi: 10.3892/mmr.2017.6142. Epub 2017 Jan 24. Beneficial effects of sulfonamide-based gallates on osteoblasts in vitro

Wang X, Cao P, Liu J, Du P, Wang Z, Chen W, Liu C, Wu Y. Med Sci Monit. 2017 Jan 4;23:46-56. 5-Aminolaevulinic Acid-Based Photodynamic Therapy Restrains Pathological Hyperplasia of Fibroblasts

Shang P, Liu W, Liu T, Zhang Y, Mu F, Zhu Z, Liang L, Zhai X, Ding Y, Li Y, Wen A. Sci Rep. 2016 Dec 23;6:39809. doi: 10.1038/srep39809. Acetyl-11-Keto-β-Boswellic Acid Attenuates Prooxidant and Profibrotic Mechanisms Involving Transforming Growth...

Ge Ws, Wang Yj, Wu Jx, Fan Jg, Chen Yw, Zhu L. Mol Med Rep. 2014 Jun;9(6):2145-51. Doi: 10.3892/Mmr.2014.2099. Epub 2014 Apr 1. ??-Catenin Is Overexpressed In Hepatic Fibrosis And Blockage Of Wnt/??-Catenin Signaling Inhibits Hepatic Stellate Cell...

Ma X, Xu L, Wang S, Chen H, Xu J, Li X, Ning G. Lab Invest. 2009 Aug;89(8):903-14. Doi: 10.1038/Labinvest.2009.51. Epub 2009 Jun 1. Loss Of Steroid Receptor Co-Activator-3 Attenuates Carbon Tetrachloride-Induced Murine Hepatic Injury And Fibrosis.

Yang L, Ni L, Duan Q, Wang X, Chen C, Chen S, Chaugai S, Zeldin Dc, Tang Jr, Wang Dw. Prostaglandins Other Lipid Mediat. 2015 Jan-Mar;116-117:64-75. Doi: 10.1016/J.Prostaglandins.2015.01.004. Epub 2015 Feb 14. Cyp Epoxygenase 2J2 Prevents Cardiac ...

Zhu B, Xu T, Yuan J, Guo X, Liu D. Plos One. 2013 Sep 19;8(9):E76282. Doi: 10.1371/Journal.Pone.0076282. Ecollection 2013. Transcriptome Sequencing Reveals Differences Between Primary And Secondary Hair Follicle-Derived Dermal Papilla Cells Of The...

Liang J, Deng X, Lin Zx, Zhao Lc, Zhang Xl. World J Gastroenterol. 2009 Sep 28;15(36):4529-37. Attenuation Of Portal Hypertension By Natural Taurine In Rats With Liver Cirrhosis.

Ge Ws, Wu Jx, Fan Jg, Wang Yj, Chen Yw. World J Gastroenterol. 2011 Sep 28;17(36):4090-8. Doi: 10.3748/Wjg.V17.I36.4090. Inhibition Of High-Mobility Group Box 1 Expression By Sirna In Rat Hepatic Stellate Cells.

Zhang H, Teng X, Liu Z, Zhang L, Liu Z. J Exp Clin Cancer Res. 2015 Feb 12;34:16. Doi: 10.1186/S13046-015-0132-Y. Gene Expression Profile Analyze The Molecular Mechanism Of Cxcr7 Regulating Papillary Thyroid Carcinoma Growth And Metastasis.

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15 Customer Q&As for Anti-Collagen I/COL1A1 Antibody Picoband™


I was wanting to use your anti-Collagen I/COL1A1 antibody for WB for human liver on frozen tissues, but I want to know if it has been validated for this particular application. Has this antibody been validated and is this antibody a good choice for human liver identification?

Verified Customer

Verified customer

Asked: 2020-04-02


You can see on the product datasheet, PB9938 anti-Collagen I/COL1A1 antibody has been tested for IHC, WB on human tissues. We have an innovator award program that if you test this antibody and show it works in human liver in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2020-04-02


Is a blocking peptide available for product anti-Collagen I/COL1A1 antibody (PB9938)?

Verified Customer

Verified customer

Asked: 2020-02-03


We do provide the blocking peptide for product anti-Collagen I/COL1A1 antibody (PB9938). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2020-02-03


We have seen staining in human skin. Do you have any suggestions? Is anti-Collagen I/COL1A1 antibody supposed to stain skin positively?

Verified Customer

Verified customer

Asked: 2019-11-28


According to literature skin does express COL1A1. According to, COL1A1 is expressed in spinal cord, spleen, brain, skin, fetal brain cortex, bone, liver, among other tissues. Regarding which tissues have COL1A1 expression, here are a few articles citing expression in various tissues:
Bone, Pubmed ID: 3340531
Brain, Pubmed ID: 15489334
Liver, Pubmed ID: 24275569
Skin, Pubmed ID: 4319110, 5529814

Boster Scientific Support

Answered: 2019-11-28


Does anti-Collagen I/COL1A1 antibody PB9938 work for WB with liver?

K. Evans

Verified customer

Asked: 2019-09-11


According to the expression profile of liver, COL1A1 is highly expressed in liver. So, it is likely that anti-Collagen I/COL1A1 antibody PB9938 will work for WB with liver.

Boster Scientific Support

Answered: 2019-09-11


I have a question about product PB9938, anti-Collagen I/COL1A1 antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?

Verified Customer

Verified customer

Asked: 2019-08-21


We do not recommend storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free PB9938 anti-Collagen I/COL1A1 antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.

Boster Scientific Support

Answered: 2019-08-21


I see that the anti-Collagen I/COL1A1 antibody PB9938 works with WB, what is the protocol used to produce the result images on the product page?

Verified Customer

Verified customer

Asked: 2019-08-09


You can find protocols for WB on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]

Boster Scientific Support

Answered: 2019-08-09


I have attached the WB image, lot number and protocol we used for liver using anti-Collagen I/COL1A1 antibody PB9938. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2019-06-21


Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2019-06-21


Would PB9938 anti-Collagen I/COL1A1 antibody work on parafin embedded sections? If so, which fixation method do you recommend we use (PFA, paraformaldehyde, other)?

Verified Customer

Verified customer

Asked: 2018-01-03


As indicated on the product datasheet, PB9938 anti-Collagen I/COL1A1 antibody as been validated on WB. It is best to use PFA for fixation because it has better tissue penetration ability. PFA needs to be prepared fresh before use. Long term stored PFA turns into formalin, as the PFA molecules congregate and become formalin.

Boster Scientific Support

Answered: 2018-01-03


We are currently using anti-Collagen I/COL1A1 antibody PB9938 for human tissue, and we are satisfied with the IHC results. The species of reactivity given in the datasheet says human. Is it possible that the antibody can work on feline tissues as well?

Verified Customer

Verified customer

Asked: 2017-12-15


The anti-Collagen I/COL1A1 antibody (PB9938) has not been validated for cross reactivity specifically with feline tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2017-12-15


Our lab were content with the WB result of your anti-Collagen I/COL1A1 antibody. However we have seen positive staining in spleen secreted using this antibody. Is that expected? Could you tell me where is COL1A1 supposed to be expressed?

Verified Customer

Verified customer

Asked: 2017-11-14


Based on literature, spleen does express COL1A1. Generally COL1A1 expresses in secreted, extracellular space, extracellular. Regarding which tissues have COL1A1 expression, here are a few articles citing expression in various tissues:
Bone, Pubmed ID: 3340531
Brain, Pubmed ID: 15489334
Liver, Pubmed ID: 24275569
Skin, Pubmed ID: 4319110, 5529814

Boster Scientific Support

Answered: 2017-11-14


Is this PB9938 anti-Collagen I/COL1A1 antibody reactive to the isotypes of COL1A1?

K. Patel

Verified customer

Asked: 2015-10-22


The immunogen of PB9938 anti-Collagen I/COL1A1 antibody is A synthetic peptide corresponding to a sequence at the C-terminus of human Collagen I (1194-1218aa AGFDFSFLPQPPQEKAHDGGRYYRA), different from the related mouse and rat sequences by four amino acids. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2015-10-22


Is there a BSA free version of anti-Collagen I/COL1A1 antibody PB9938 available?

P. Bhatt

Verified customer

Asked: 2015-07-17


Thank you for your recent telephone inquiry. I can confirm that some lots of this anti-Collagen I/COL1A1 antibody PB9938 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.

Boster Scientific Support

Answered: 2015-07-17


We want to test anti-Collagen I/COL1A1 antibody PB9938 on human liver for research purposes, then I may be interested in using anti-Collagen I/COL1A1 antibody PB9938 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

E. Anderson

Verified customer

Asked: 2014-08-27


The products we sell, including anti-Collagen I/COL1A1 antibody PB9938, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2014-08-27


Thanks for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for liver using anti-Collagen I/COL1A1 antibody PB9938. Let me know if you need anything else.

D. Taylor

Verified customer

Asked: 2014-01-08


I appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2014-01-08


We ordered your anti-Collagen I/COL1A1 antibody for WB on bone in a previous project. I am using human, and I plan to use the antibody for IHC next. you antibody examining bone as well as spleen in our next experiment. Could you please give me some suggestion on which antibody would work the best for IHC?

A. Collins

Verified customer

Asked: 2013-12-09


I looked at the website and datasheets of our anti-Collagen I/COL1A1 antibody and it seems that PB9938 has been validated on human in both WB and IHC. Thus PB9938 should work for your application. Our Boster satisfaction guarantee will cover this product for IHC in human even if the specific tissue type has not been validated. We do have a comprehensive range of products for IHC detection and you can check out our website to find out more information about them.

Boster Scientific Support

Answered: 2013-12-09



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