- Table of Content
|peptidase M14 family|
|Sequence:||4; NC_000004.12 (165379008..165498547)|
Isoform 2, but not isoform 1, is overexpressed in hepatocellular carcinoma (at protein level), as well as in other tumors, including pheochromocytomas and paragangliomas.
[Isoform 1]: Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted. Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions.; [Isoform 2]: Nucleus.