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- Table of Contents
Transcription factor E2F3 Antibodies
AND E2F3 ELISA kits, Transcription factor E2F3 Proteins
Many biological assays use antibodies to detect Transcription factor E2F3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transcription factor E2F3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transcription factor E2F3 antibodies...
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E2F3 Infographic by Boster Bio
All E2F3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
WB
$370
Cat # PA2142
100 μg/vial
Cat # PA2142
100 μg/vial
Human, Mouse
ELISA, IF, IHC-P, WB
$481
Cat # A03068-1
0.1 mg
Cat # A03068-1
0.1 mg
Anti-E2F3 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A03068-4
100 μg/vial
Cat # A03068-4
100 μg/vial
E2F3 Overview
Facts about Transcription factor E2F3.
Transcription factor E2F3 (E2F3)
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a variety of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase.
E2F3 binds specifically to RB1 in a cell-cycle dependent way. Inhibits adipogenesis, likely through the repression of CEBPA binding to its target gene promoters (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | E2F3 |
| Uniprot: | O00716 |
| Entrez: | 1871 |
Family
| Belongs to: |
|---|
| E2F/DP family |
Alternative Names
DKFZp686C18211; E2F transcription factor 3; E2F-3; KIAA0075; MGC104598; transcription factor E2F3
Molecular Weight
Mass (kDA):
49.162 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p22.3 |
| Sequence: | 6; NC_000006.12 (20401879..20493714) |
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Retinoblastoma
- Malignant Neoplasms
- Carcinoma
- Cell Transformation, Neoplastic
- Hyperplasia
- Malignant Neoplasm Of Prostate
- Prostatic Neoplasms
- Malignant Neoplasm Of Breast
- Bladder Neoplasm
- Malignant Neoplasm Of Urinary Bladder
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- HELLS
- L3MBTL3
- MSH2
- RB1
Pathways
- Cell Cycle
- Cell Proliferation
- Cell Growth
- S Phase
- Dna Replication
- Mitosis
- Cell Cycle Arrest
- Cell Division
- Senescence
- Methylation
- Dna Repair
- Induction Of Apoptosis
- Cell Death
PTMs
- Phosphorylation
- Methylation
Research Areas
- Cell Cycle and Replication
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/E2F3
bosterbio.com/bosterbio-gene-info-cards/E2F3
References
PMID: 8246996 by Lees J.A., et al. The retinoblastoma protein binds to a family of E2F transcription factors.
PMID: 15716352 by Novy M., et al. EAPP, a novel E2F binding protein that modulates E2F-dependent transcription.
2 Publications of Boster Transcription factor E2F3 Antibodies & ELISA Kits
- PubMed ID: 20049626, Wang Py, Li Yj, Zhang S, Li Zl, Yue Z, Xie N, Xie Sy. Mol Cell Biochem. 2010 Jun...
- PubMed ID: 20428827, Xie Sy, Li Yj, Wang Py, Jiao F, Zhang S, Zhang Wj. Oncol Rep. 2010 Jun;23(6):169...
*More publications can be found for each product on its corresponding product page