MYD88 Antibodies

Myeloid differentiation primary response protein MyD88 (MYD88)

Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response (PubMed:15361868, PubMed:18292575). Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:15361868, PubMed:24316379, PubMed:19506249).

Increases IL-8 transcription (PubMed:9013863). Involved in IL-18-mediated signaling pathway.

Gene Information

Human
Gene Name:	MYD88
Uniprot:	Q99836
Entrez:	4615

Family

Belongs to:
No superfamily

Alternative Names

MyD88; MYD88D; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88

Molecular Weight

Mass (kDA):
33.233 kDA

Genomic Context

Human
Location:	3p22.2
Sequence:	3; NC_000003.12 (38138661..38143022)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

• Inflammation
• Innate Immune Response
• Infective Disorder
• Inflammatory Response
• Bacterial Infections
• Pneumonia
• Neoplasms
• Systemic Infection
• Virus Diseases
• Malignant Neoplasms
• Autoimmune Reaction
• Tuberculosis
• Colitis

• Autoimmune Diseases
• Salmonella Infections
• Cell Invasion
• Autoimmunity
• Fibrosis
• Tissue Adhesions
• Influenza

Interacting Proteins

• CYTH2
• DOCK8
• FADD
• HDAC6
• IRAK1

• IRAK4
• SARM1
• SIAH1
• SMAD3
• SPOP

• STAP2
• TIRAP
• TLR2
• TLR4
• TNFRSF13B

• TXN
• USP7

Pathways

• Immune Response
• Secretion
• Cytokine Production
• Innate Immune Response
• Pathogenesis
• Inflammatory Response
• Cell Activation
• Cell Death
• Cell Proliferation
• Virulence
• Phagocytosis
• Adaptive Immune Response
• Macrophage Activation

• Localization
• Cytokine Secretion
• Rna Interference
• Response To Lipopolysaccharide
• Chemokine Production
• Cell Differentiation
• T Cell Proliferation

PTMs

• Phosphorylation
• Cleavage
• Methylation
• Ubiquitination
• Glycosylation
• Phosphorothioation
• Acylation
• Acetylation
• Oxidation
• Dephosphorylation

• Ribosylation
• Biotinylation
• Nitration
• Sulphation
• Nitrosylation
• Citrullination
• Gpi Anchoring
• Farnesylation
• Deglycosylation
• Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYD88

Best Uses Of The MYD88 Marker From Boster Bio

In this article, we'll review the various types of samples as well as the validation of Boster Bio ELISA kits. It also provides information on other products offered by the company including BeNeLux deliveries. Below are the types of samples that Boster Bio ELISA kit has been tested for. We will also discuss the various types and uses of MYD88 detection kits.

Boster Bio ELISA kits are tested and validated

This kit has been validated for the MYD88 marker. Boster Bio offers high-affinity primary antibodies that have been extensively cited in the research community over the past 25 years. Boster Bio antibodies have been validated for use in ELISA, immunohistochemistry, and Western blotting. ELISA kits for a variety of cell types, including breast carcinoma cells, are validated for the MYD88 marker.

Picokine(tm) the ELISA kit, is highly sensitive and has a single-digit picogram sensitivity. The ELISA kit can be tested at 37°C, and will keep its sensitivity for 12 months. It comes with enough reagents that can carry out at least 96 tests. Picokine(tm) is an ELISA kit has been tested for multiple antigens. It is extremely sensitive. It is available through Tebubio in Europe.

ELISAs perform in the same way as other immunoassay techniques. ELISA makes use of specific antibodies to attach to the antigen target. The detection system then determines whether the antigen is present. Boster Bio has developed a high-affinity antibody coating that improves the assay's sensitivity. Boster Bio ELISA kit validations for the MYD88 marker aren't uncommon.

They are tested for a wide range of samples

The MYD88 markers from Boster Bio are based on an extensive array of antibodies which have been thoroughly tested against a broad range of samples. Boster Bio antibodies are highly specific due to their standard design of the immunogen and panels of 250 tissues. Quantitative validations can also be performed for specific antibodies. High doses of BYF were used to restore MyD88 levels in the kidney tissues. The BYF treatment reduced renal fibrosis and reduced inflammation.

They are available in picogram sensitivity

Picokine(tm) ELISA kits contain the necessary reagents to perform the assay. This method is based on plates and detects molecules using antibodies that interact with enzymes in order to quantify the results. There are various types of ELISA. The principle of interaction between antibodies and antigens differs for each format. Boster's Picokine(tm) ELISA kits contain high-affinity antibodies that detect proteins in their native form. They are also tested for superfamilies and immunogenicity.

The Boster Bio Anti-MyD88-PTGS2 antibody is part of the Picoband(tm) antibody catalog. Its sensitivity was evaluated using mouse, human and MyD88 proteins from rats. Its formula is made up of 5 mg bovine serum albumin, 0.9 mg of sodium chloride and 0.2 mg of sodium phosphate. Its sensitivity was tested against a variety of over 250 cells and untransfected lines.