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- Table of Contents
von Willebrand factor Antibodies
AND VWF ELISA kits, von Willebrand factor Proteins
Many biological assays use antibodies to detect von Willebrand factor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with von Willebrand factor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop von Willebrand factor antibodies...
Designing a Western blot for von Willebrand factor? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the VWF Western Blot GuideVWF Infographic by Boster Bio
All VWF Products
Product
Figures
Specificity
Applications
Price
Anti-Von Willebrand Factor/VWF Antibody Picoband®
40 Citations
Mouse, Rat
IF, IHC, WB
$370
Cat # PB9273
100 μg/vial
Cat # PB9273
100 μg/vial
Anti-Von Willebrand Factor/VWF Antibody Picoband®
21 Citations
Human
Flow Cytometry, IHC, IHC-F, ICC, WB
$370
Cat # PB9062
100 μg/vial
Cat # PB9062
100 μg/vial
Human VWF-A2/VWF ELISA Kit PicoKine®
2 Citations
Human
ELISA
$499
Cat # EK1743
96 wells/kit, with removable strips.
Cat # EK1743
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00270-6
20μL, 40μL, 100μL, 200μL
Cat # M00270-6
20μL, 40μL, 100μL, 200μL
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00270-5
100 μg
Cat # M00270-5
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00270-4
100 μg
Cat # M00270-4
100 μg
Human
$960
Cat # LS007450
20 µg, 100 µg
Cat # LS007450
20 µg, 100 µg
VWF Overview
Facts about von Willebrand factor.
von Willebrand factor (VWF)
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also functions as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | VWF |
| Uniprot: | P04275 |
| Entrez: | 7450 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
coagulation factor VIII VWF; F8; F8VWF; von Willebrand factor; VWD; vWF
Molecular Weight
Mass (kDA):
309.265 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12p13.31 |
| Sequence: | 12; NC_000012.12 (5948877..6124670, complement) |
Tissue Specificity
Plasma.
Subcellular Localizations
Secreted. Secreted, extracellular space, extracellular matrix. Localized to storage granules.
Diseases
- Von Willebrand Disease
- Hemorrhage
- Tissue Adhesions
- Thrombosis
- Bleeding Tendency
- Purpura, Thrombotic Thrombocytopenic
- Purpura
- Thrombocytopenic Purpura
- Hemophilia A
- Thrombus
- Inflammation
- Raynaud Disease
- Blood Coagulation Disorders
Interacting Proteins
- ADAMTS13
- F8
- GP1BA
- OPTN
Pathways
- Coagulation
- Platelet Aggregation
- Hemostasis
- Secretion
- Proteolysis
- Pathogenesis
- Platelet Activation
- Angiogenesis
- Exocytosis
- Fibrinolysis
- Localization
- Vasoconstriction
- Cell Adhesion
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
- Reduction
- Oxidation
- Dephosphorylation
- Biotinylation
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VWF
bosterbio.com/bosterbio-gene-info-cards/VWF
References
PMID: 3489923 by Bonthron D., et al. Nucleotide sequence of pre-pro-von Willebrand factor cDNA.
PMID: 2584182 by Mancuso D.J., et al. Structure of the gene for human von Willebrand factor.
53 Publications of Boster von Willebrand factor Antibodies & ELISA Kits
- PubMed ID: PMID:29118911, Fibroblast growth factor 21 delayed endothelial replicative senescence and prote...
- PubMed ID: PMID:26191130, Calcium signaling is implicated in the diffuse axonal injury of brain stem
- PubMed ID: 10.3892/or_00000545, Identification and characterization of cancer stem-like cells from primary carci...
- PubMed ID: 10.3892/or.16.5.1021, Histological type of oncogenity and expression of cell cycle genes in tumor cell...
- PubMed ID: 10.3892/mmr.2014.2961, Paxillin regulates vascular endothelial growth factor A-induced in vitro angiog...
- PubMed ID: 10.3892/etm.2014.1780, Effects of propranolol and isoproterenol on infantile hemangioma endothelial cel...
- PubMed ID: 10.3892/etm.2014.1774, Construction of tissue‑engineered bone using a bioreactor and platelet‑rich ...
- PubMed ID: 10.3748/wjg.v13.i48.6558, PlexinA1 expression in gastric carcinoma and its relationship with tumor angioge...
- PubMed ID: 10.2147/IJN.S238478, A Three-Dimensional Printed Polycaprolactone Scaffold Combined with Co-Axially E...
- PubMed ID: 10.1371/journal.pone.0132743, IFI6 Inhibits Apoptosis via Mitochondrial-Dependent Pathway in Dengue Virus 2 In...
- PubMed ID: 10.12659/MSM.915442, Identification and Analysis of Differentially Expressed Genes in Human Saphenous...
- PubMed ID: 10.1186/s13287-021-02280-2, Sodium alginate-bioglass-encapsulated hAECs restore ovarian function in prematur...
- PubMed ID: 10.1186/s13287-021-02260-6, Transplantation of human amniotic epithelial cells promotes morphological and fu...
- PubMed ID: 10.1186/s12906-020-02968-7, The protective effects of angelica organic acid against ox-LDL-induced autophagy...
- PubMed ID: 10.1155/2019/6708435, Combining ECM Hydrogels of Cardiac Bioactivity with Stem Cells of High Cardiomyo...
- PubMed ID: 10.1097/SHK.0b013e3180310f3a, ANGIOTENSIN-CONVERTING ENZYME INHIBITOR CAPTOPRIL PREVENTS OLEIC ACID-INDUCED SE...
- PubMed ID: 10.1097/BCR.0000000000000617, Resolvin D2 Limits Secondary Tissue Necrosis After Burn Wounds in Rats
- PubMed ID: 10.1021/acsami.5b01234, RoY Peptide-Modified Chitosan-Based Hydrogel to Improve Angiogenesis and Cardiac...
- PubMed ID: 10.1016/j.yexmp.2005.07.004, Mesenchymal stem cells derived from bone marrow favor tumor cell growth in vivo
- PubMed ID: 10.1016/j.sjbs.2015.06.021, The effect and action mechanism of resveratrol on the vascular endothelial cell ...
- PubMed ID: 10.1016/j.diff.2018.07.001, Comparison of phenotypes and transcriptomes of mouse skin-derived precursors and...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page