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- Table of Contents
Annexin A1 Antibodies
AND ANXA1 ELISA kits, Annexin A1 Proteins
Many biological assays use antibodies to detect Annexin A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Annexin A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Annexin A1 antibodies...
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ANXA1 Infographic by Boster Bio
All ANXA1 Products
Product
Figures
Specificity
Applications
Price
Anti-Annexin A1/ANXA1 Antibody Picoband®
4 Citations 19 Q&As
Human, Monkey
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PA1006
100 μg/vial
Cat # PA1006
100 μg/vial
Anti-Annexin A1/ANXA1 Antibody Picoband®
2 Citations 16 Q&As
Human, Monkey, Rat
IHC, WB
$370
Cat # PB9127
100 μg/vial
Cat # PB9127
100 μg/vial
Human Annexin A1 ELISA Kit PicoKine®
5 Citations 6 Q&As
Human
ELISA
$499
Cat # EK1745
96 wells/kit, with removable strips.
Cat # EK1745
96 wells/kit, with removable strips.
Human Annexin A1 PicoKine® Quick ELISA Kit
1 Citations
Human
ELISA
$499
Cat # FEK1745
96 wells/kit, with removable strips.
Cat # FEK1745
96 wells/kit, with removable strips.
Human, Mouse, Rat
IF, IHC, WB
$523
Cat # M01451-2
100 µl
Cat # M01451-2
100 µl
Human
Flow Cytometry, IHC, WB
$370
Cat # M01451-3
100 μg/vial
Cat # M01451-3
100 μg/vial
ANXA1 Overview
Facts about Annexin A1.
Annexin A1 (ANXA1)
Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti inflammatory activity (PubMed:8425544).
Plays a role in glucocorticoid-mediated down- regulation of the early phase of the inflammatory response (By similarity). Promotes resolution of inflammation and wound healing (PubMed:25664854).
Gene Information
| Human | |
|---|---|
| Gene Name: | ANXA1 |
| Uniprot: | P04083 |
| Entrez: | 301 |
Family
| Belongs to: |
|---|
| annexin family |
Alternative Names
Annexin A1; annexin I (lipocortin I); Annexin I; Annexin-1; ANX1; ANXA1; Calpactin II; calpactin-2; chromobindin-9; Lipocortin I; LPC1; LPC1annexin-1; p35; Phospholipase A2 inhibitory protein
Molecular Weight
Mass (kDA):
38.714 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q21.13 |
| Sequence: | 9; NC_000009.12 (73151865..73170393) |
Tissue Specificity
Detected in resting neutrophils (PubMed:10772777). Detected in peripheral blood T-cells (PubMed:17008549). Detected in extracellular vesicles in blood serum from patients with inflammatory bowel disease, but not in serum from healthy donors (PubMed:25664854). Detected in placenta (at protein level) (PubMed:2532504). Detected in liver.
Subcellular Localizations
Nucleus. Cytoplasm. Cell projection, cilium. Cell membrane. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Basolateral cell membrane. Apical cell membrane. Lateral cell membrane. Secreted. Secreted, extracellular space. Cell membrane; Peripheral membrane protein; Extracellular side. Secreted, extracellular exosome. Cytoplasmic vesicle, secretory vesicle lumen. Cell projection, phagocytic cup. Early endosome. Cytoplasmic vesicle membrane; Peripheral membrane protein. Secreted, at least in part via exosomes and other secretory vesicles. Detected in exosome
Diseases
- Malignant Neoplasms
- Neoplasms
- Inflammation
- Carcinoma
- Tissue Adhesions
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Adenocarcinoma
- Mammary Neoplasms
- Pituitary Diseases
- Cell Transformation, Neoplastic
- Carcinogenesis
- Malignant Squamous Cell Neoplasm
Interacting Proteins
- IKBKG
- RIPK1
Pathways
- Secretion
- Localization
- Cell Migration
- Cell Proliferation
- Inflammatory Response
- Cell Adhesion
- Cell Cycle
- Cell Growth
- Transport
- Cell Differentiation
- Immune Response
- Wound Healing
- Cell Death
PTMs
- Phosphorylation
- Cleavage
- Acetylation
Research Areas
- Protein Kinase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANXA1
bosterbio.com/bosterbio-gene-info-cards/ANXA1
References
PMID: 2936963 by Wallner B.P., et al. Cloning and expression of human lipocortin, a phospholipase A2 inhibitor with potential anti-inflammatory activity.
PMID: 1832554 by Kovacic R.T., et al. Correlation of gene and protein structure of rat and human lipocortin I.
8 Publications of Boster Annexin A1 Antibodies & ELISA Kits
- PubMed ID: 10.3892/ol.2012.959, Annexin A1, A2, A4 and A5 play important roles in breast cancer, pancreatic canc...
- PubMed ID: 10.1038/s41598-020-77902-5, Defective membrane repair machinery impairs survival of invasive cancer cells
- PubMed ID: 10.1016/j.bbamcr.2016.06.003, Membrane repair of human skeletal muscle cells requires Annexin-A5
- PubMed ID: 10.1007/s10534-010-9368-3, Proteomic analysis of lanthanum citrate-induced apoptosis in human cervical carc...
- PubMed ID: 30242262, Annexin A1, A2, A4 and A5 play important roles in breast cancer, pancreatic canc...
- PubMed ID: 29970967, Low Annexin A1 expression predicts benefit from induction chemotherapy in oral c...
- PubMed ID: 23587191, Annexin A1 protein regulates the expression of PMVEC cytoskeletal proteins in CB...
- PubMed ID: 26211001, Mohamed Hg,, Idris Sb, Ahmed Mf, ??str??m An, Mustafa K, Ibrahim So, Mustafa M. ...
*More publications can be found for each product on its corresponding product page