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- Table of Contents
Cadherin-1 Antibodies
AND CDH1 ELISA kits, Cadherin-1 Proteins
Many biological assays use antibodies to detect Cadherin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cadherin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cadherin-1 antibodies...
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CDH1 Infographic by Boster Bio
All CDH1 Products
Product
Figures
Specificity
Applications
Price
Anti-E Cadherin 1/CDH1 Antibody Picoband®
63 Citations 6 Q&As
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # PB9561
100 μg/vial
Cat # PB9561
100 μg/vial
Rat E-Cadherin/CDH1/Cadherin-1 ELISA Kit PicoKine®
1 Citations 10 Q&As
Rat
ELISA
$499
Cat # EK1434
96 wells/kit, with removable strips.
Cat # EK1434
96 wells/kit, with removable strips.
Human E-Cadherin/CDH1/Cadherin-1 ELISA Kit PicoKine®
5 Citations 10 Q&As
Human
ELISA
$499
Cat # EK0561
96 wells/kit, with removable strips.
Cat # EK0561
96 wells/kit, with removable strips.
Mouse E-Cadherin/CDH1/Cadherin-1 ELISA Kit PicoKine®
5 Citations 8 Q&As
Mouse
ELISA
$499
Cat # EK0562
96 wells/kit, with removable strips.
Cat # EK0562
96 wells/kit, with removable strips.
Anti-E Cadherin Rabbit Monoclonal Antibody
5 Citations
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00063-4
100 μl
Cat # M00063-4
100 μl
Anti-pan Cadherin 1 CDH1 Rabbit Monoclonal Antibody
2 Citations 15 Q&As
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00063-1
100 μl
Cat # M00063-1
100 μl
Anti-E Cadherin 1 CDH1 Antibody Picoband® (monoclonal, 9G2)
10 Citations 15 Q&As
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00063-2
100 μg/vial
Cat # M00063-2
100 μg/vial
Anti-E-Cadherin 1 (CDH1) Rabbit Monoclonal Antibody, Clone#RM244
1 Citations 16 Q&As
Human
IHC, WB
$449
Cat # M00063-3
100ul
Cat # M00063-3
100ul
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$405
Cat # A00063-1
100ul
Cat # A00063-1
100ul
Anti-E-cadherin/Cdh1 Antibody Picoband®
2 Citations
Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A00063-3
100 µg/vial
Cat # A00063-3
100 µg/vial
Mouse
ELISA
$499
Cat # FEK0562
96 wells/kit, with removable strips.
Cat # FEK0562
96 wells/kit, with removable strips.
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00063-6
100 μg
Cat # M00063-6
100 μg
Mouse
ELISA
$500
Cat # EZ0562
5 plates/kit
Cat # EZ0562
5 plates/kit
Zebrafish
IHC, WB
$470
Cat # AZQ90Z37
100 μg/vial
Cat # AZQ90Z37
100 μg/vial
CDH1 Overview
Facts about Cadherin-1.
Cadherin-1 (CDH1)
Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a powerful invasive suppressor role.
Gene Information
| Human | |
|---|---|
| Gene Name: | CDH1 |
| Uniprot: | P12830 |
| Entrez: | 999 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Arc-1; CAD1; cadherin 1, E-cadherin (epithelial); cadherin 1, type 1, E-cadherin (epithelial); Cadherin-1; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324 antigen; CD324; CDH1; CDHE; cell-CAM 120/80; Cell-CAM120/80; ECAD; ECadherin; E-Cadherin; Epithelial cadherin; LCAM; L-CAM; UVOE-Cadherin; Uvomorulin
Molecular Weight
Mass (kDA):
97.456 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q22.1 |
| Sequence: | 16; NC_000016.10 (68737292..68835537) |
Tissue Specificity
Non-neural epithelial tissues.
Subcellular Localizations
Cell junction, adherens junction. Cell membrane; Single-pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm. Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Neoplasm Of Stomach
- Stomach Neoplasms
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Tissue Adhesions
- Neoplasm Metastasis
- Carcinogenesis
- Cell Invasion
- Adenocarcinoma
Interacting Proteins
- Cbll1
- CDC27
- CTNNA1
- CTNNB1
- ECT2
- EGFR
- FGFR1
- LIMA1
- PPP1CA
- PRKD1
Pathways
- Methylation
- Cell Cycle
- Mitosis
- Dna Methylation
- Anaphase
- Proteolysis
- Cell Adhesion
- Pathogenesis
- Localization
- S Phase
- Cell Proliferation
- Cell Division
- Cell-cell Adhesion
PTMs
- Methylation
- Phosphorylation
- Ubiquitination
- Demethylation
- Dephosphorylation
- Cleavage
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDH1
bosterbio.com/bosterbio-gene-info-cards/CDH1
References
PMID: 8459805 by Bussemakers M.J.G., et al. Molecular cloning and characterization of the human E-cadherin cDNA.
PMID: 8127895 by Oda T., et al. E-cadherin gene mutations in human gastric carcinoma cell lines.
73 Publications of Boster Cadherin-1 Antibodies & ELISA Kits
- PubMed ID: PMID:30210698, Identification and differentiation therapy strategy of pterygium in vitro
- PubMed ID: PMID:26722422, Wnt/β-catenin pathway is required for epithelial to mesenchymal transition in C...
- PubMed ID: PMID:26617787, RAC1 overexpression promotes the proliferation, migration and epithelial-mesench...
- PubMed ID: PMID:26617724, Expression of RKIP, E-cadherin and NF-kB p65 in esophageal squamous cell carcino...
- PubMed ID: 10.7150/jca.49138, LINC00184 involved in the regulatory network of ANGPT2 via ceRNA mediated miR-14...
- PubMed ID: 10.4149/neo_2016_603, Silencing of ATPase family AAA domain-containing protein 2 inhibits migration an...
- PubMed ID: 10.3892/ijo.2016.3343, Overexpression of SDF-1 activates the NF-κB pathway to induce epithelial to mes...
- PubMed ID: 10.3892/ijmm.2021.5071, Microrchidia family CW‑type zinc finger 2 promotes the proliferation, invasio...
- PubMed ID: 10.3760/cma.j.issn.0366-6999.2011.23.036, Effect of anaphylatoxin C3a, C5a on the tubular epithelial-myofibroblast transdi...
- PubMed ID: 10.3748/wjg.v18.i47.7070, Connective tissue growth factor is overexpressed in human hepatocellular carcino...
- PubMed ID: 10.2147/OTT.S93738, Overexpression of Livin promotes migration and invasion of colorectal cancer cel...
- PubMed ID: 10.1186/s12935-020-1150-1, Hsa_circ_0137008 suppresses the malignant phenotype in colorectal cancer by acti...
- PubMed ID: 10.1177/0885328216688337, Evaluation on biological compatibility of carboxymethyl chitosan as biomaterials...
- PubMed ID: 10.1111/bcpt.12616, Placental Growth Factor Triggers Epithelial‐to‐Mesenchymal Transition‐like...
- PubMed ID: 10.1038/labinvest.2013.108, All-transretinoic acid ameliorates bleomycin-induced lung fibrosis by downregula...
- PubMed ID: 10.1038/bjc.2015.444, Regulator of cullins-1 expression knockdown suppresses the malignant progression...
- PubMed ID: 10.1016/j.placenta.2021.06.004, Iodothyronine deiodinase 2 (DiO2) regulates trophoblast cell line cycle, invasio...
- PubMed ID: 10.1016/j.jsps.2021.12.009, Reposition of the anti-inflammatory drug diacerein in an in-vivo colorectal canc...
- PubMed ID: 10.1016/j.jff.2021.104661, Genetically encoded probiotic EcN 1917 alleviates alcohol-induced acute liver in...
- PubMed ID: 10.1016/j.carbpol.2017.06.072, Preparation and pharmacological evaluation of norcantharidin-conjugated carboxym...
- PubMed ID: 10.1016/j.apjtm.2016.04.022, Experiment research of cisplatin implants inhibiting transplantation tumor growt...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page