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- Table of Contents
Cadherin-2 Antibodies
AND CDH2 ELISA kits, Cadherin-2 Proteins
Many biological assays use antibodies to detect Cadherin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cadherin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cadherin-2 antibodies...
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CDH2 Infographic by Boster Bio
All CDH2 Products
Product
Figures
Specificity
Applications
Price
Human N-Cadherin-2 CDH2 CD325 ELISA Kit PicoKine®
1 Citations 8 Q&As
Human
ELISA
$499
Cat # EK0669
96 wells/kit, with removable strips.
Cat # EK0669
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1155
96 wells/kit, with removable strips.
Cat # EK1155
96 wells/kit, with removable strips.
Rat N-Cadherin-2 CDH2 CD325 ELISA Kit PicoKine®
2 Citations 7 Q&As
Rat
ELISA
$499
Cat # EK1156
96 wells/kit, with removable strips.
Cat # EK1156
96 wells/kit, with removable strips.
Anti-N-Cadherin-2 CDH2 CD325-Antibody Picoband®
50 Citations 7 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$370
Cat # PA1328
100 μg/vial
Cat # PA1328
100 μg/vial
Canine
ELISA
$499
Cat # EK0669-CN
96 wells/kit, with removable strips.
Cat # EK0669-CN
96 wells/kit, with removable strips.
Pig
ELISA
$499
Cat # EK0669-PO
96 wells/kit, with removable strips.
Cat # EK0669-PO
96 wells/kit, with removable strips.
Rabbit
ELISA
$499
Cat # EK0669-RB
96 wells/kit, with removable strips.
Cat # EK0669-RB
96 wells/kit, with removable strips.
Monkey
ELISA
$499
Cat # EK0669-PR
96 wells/kit, with removable strips.
Cat # EK0669-PR
96 wells/kit, with removable strips.
Human, Mouse, Rat
IHC, WB
$370
Cat # M01577-1
100 μl
Cat # M01577-1
100 μl
Human
WB
$449
Cat # M01577-2
100uL
Cat # M01577-2
100uL
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$405
Cat # A01577-1
100ul
Cat # A01577-1
100ul
Anti-N Cadherin/CDH2 Antibody Picoband®
21 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01577-3
100 μg/vial
Cat # A01577-3
100 μg/vial
Dog, Human, Monkey, Mouse, Rat
Flow Cytometry, IHC, WB
$523
Cat # M01577-3
100 µl
Cat # M01577-3
100 µl
Human, Mouse
ELISA, IHC, WB
$146
Cat # M01577-6
20μL, 40μL, 100μL, 200μL
Cat # M01577-6
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01577-7
20μL, 40μL, 100μL, 200μL
Cat # M01577-7
20μL, 40μL, 100μL, 200μL
CDH2 Overview
Facts about Cadherin-2.
Cadherin-2 (CDH2)
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 could be involved in neuronal recognition mechanism.
Gene Information
| Human | |
|---|---|
| Gene Name: | CDH2 |
| Uniprot: | P19022 |
| Entrez: | 1000 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
cadherin 2, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal); Cadherin-2; CD325 antigen; CD325; CDH2; CDHNcalcium-dependent adhesion protein, neuronal; CDw325; NCadherin; N-Cadherin; NCADN-cadherin 1; Neural cadherin; neural-cadherin
Molecular Weight
Mass (kDA):
99.809 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 18q12.1 |
| Sequence: | 18; NC_000018.10 (27932878..28177130, complement) |
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Cell membrane, sarcolemma. Cell junction. Cell surface. Colocalizes with TMEM65 at the intercalated disk in cardiomyocytes. Colocalizes with OBSCN at the intercalated disk and at sarcolemma in cardiomyocytes.
Diseases
- Tissue Adhesions
- Neoplasms
- Malignant Neoplasms
- Neoplasm Metastasis
- Cell Invasion
- Carcinoma
- Neoplasm Invasiveness
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
- Cell Transformation, Neoplastic
- Adenocarcinoma
- Mammary Neoplasms
- Melanoma
Interacting Proteins
- CTNNB1
- JUP
Pathways
- Cell Adhesion
- Cell-cell Adhesion
- Localization
- Cell Migration
- Cell Proliferation
- Cell Motility
- Cell Cycle
- Epithelial To Mesenchymal Transition
- Cell Growth
- Spermatogenesis
- Pathogenesis
- Methylation
- Cell Differentiation
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Biotinylation
Research Areas
- Cancer
- Cell Cycle and Replication
- Cellular Markers
- Extracellular Matrix
- Plasma Membrane Markers
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDH2
bosterbio.com/bosterbio-gene-info-cards/CDH2
References
PMID: 2216790 by Reid R.A., et al. Human N-cadherin: nucleotide and deduced amino acid sequence.
PMID: 1500442 by Salomon D., et al. Extrajunctional distribution of N-cadherin in cultured human endothelial cells.
35 Publications of Boster Cadherin-2 Antibodies & ELISA Kits
- PubMed ID: PMID:26722422, Wnt/β-catenin pathway is required for epithelial to mesenchymal transition in C...
- PubMed ID: PMID:26617787, RAC1 overexpression promotes the proliferation, migration and epithelial-mesench...
- PubMed ID: 10.3892/ijmm.2020.4559, Altered expression of glycoprotein non‑metastatic melanoma protein B in the di...
- PubMed ID: 10.3892/etm.2013.1431, Expression of N‑cadherin proteins in myocardial hypertrophy in rats
- PubMed ID: 10.3390/ijms222010930, TMEM16A, a Homoharringtonine Receptor, as a Potential Endogenic Target for Lung ...
- PubMed ID: 10.3389/fphar.2021.643489, Inhibition of TMEM16A by Natural Product Silibinin: Potential Lead Compounds for...
- PubMed ID: 10.1139/bcb-2017-0074, The CXCL12–CXCR4 axis promotes migration, invasiveness, and EMT in human papil...
- PubMed ID: 10.1080/09168451.2017.1356216, Kallikrein-related peptidase 4 contributes to the tumor metastasis of oral squam...
- PubMed ID: 10.1016/j.urolonc.2019.03.001, sE-cadherin is upregulated in serum of patients with renal cell carcinoma and pr...
- PubMed ID: 10.1002/path.4443, MiR‐506 inhibits multiple targets in the epithelial‐to‐mesenchymal transit...
- PubMed ID: 32519176, Piao HY,Guo S,Wang Y,Zhang J.Exosome-transmitted lncRNA PCGEM1 promotes invasive...
- PubMed ID: 32236569, Zheng Y,Huang C,Yang X,Zhang Z.Altered expression of glycoprotein non‑metastat...
- PubMed ID: 33069797, Shi R,Liu L,Wang F,He Y,Niu Y,Wang C,Zhang X,Zhang X,Zhang H,Chen M,Wang Y.Downr...
- PubMed ID: 32611283, Xu H,Yu B,Shen W,Jin C,Wang L,Xi Y.Over-expression of long non-coding RNA ZEB2-A...
- PubMed ID: 32319604, Jia X, Wang H,Li Z,Yan J,Guo Y,Zhao W,Gao L,Wang B,Jia Y.HER4 promotes the progr...
- PubMed ID: 32735882, Lu N,Piao MH,Feng CS,Yuan Y.Isoflurane promotes epithelial-to-mesenchymal transi...
- PubMed ID: 32158357, Yang Z,Zhang J,Lu D,Sun Y, Zhao X,Wang X,Zhou W,He Q,Jiang Z.Hsa_circ_0137008 su...
- PubMed ID: 30399572, Expression of N%u2011cadherin proteins in myocardial hypertrophy in rats
- PubMed ID: 30086384, Expression of N-cadherin in myocardial tissues during the development of a rat h...
- PubMed ID: 27599468, Ionizing radiation promotes migration and invasion of cancer cells through trans...
- PubMed ID: 30016968, Ube2v1-mediated ubiquitination and degradation of Sirt1 promotes metastasis of c...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page