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- Table of Contents
Prothrombin Antibodies
AND F2 ELISA kits, Prothrombin Proteins
Many biological assays use antibodies to detect Prothrombin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prothrombin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prothrombin antibodies...
Designing a Western blot for Prothrombin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the F2 Western Blot GuideF2 Infographic by Boster Bio
All F2 Products
Product
Figures
Specificity
Applications
Price
Anti-PAR2 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01081
100 μl/vial
Cat # M01081
100 μl/vial
Anti-Prothrombin/F2 Antibody Picoband®
2 Citations
Human
ELISA, Flow Cytometry, IHC, ICC, WB
$370
Cat # A00044
100 μg/vial
Cat # A00044
100 μg/vial
Mouse
ELISA
$499
Cat # EK1713
96 wells/kit, with removable strips.
Cat # EK1713
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK1712
96 wells/kit, with removable strips.
Cat # EK1712
96 wells/kit, with removable strips.
Human
IHC, WB
$370
Cat # M00044-2
100 μg/vial
Cat # M00044-2
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # M00044-3
100 μg/vial
Cat # M00044-3
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A03352-1
100 μg/vial
Cat # A03352-1
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1668
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1668
1 kit, containing one 96-well plate and all necessary reagents
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00121-4
100 μg
Cat # M00121-4
100 μg
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A03352-2
100 μg/vial
Cat # A03352-2
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01081-3
100 μg
Cat # M01081-3
100 μg
Human, Mouse, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01081-2
100 μg
Cat # M01081-2
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01081-1
100 μg
Cat # M01081-1
100 μg
SDS-PAGE
$250
Cat # PROTQ61247
Starting from 10ug
Cat # PROTQ61247
Starting from 10ug
Human
$628
Cat # LS005737
20 µg, 100 µg
Cat # LS005737
20 µg, 100 µg
Human
$628
Cat # LS009002
20 µg, 100 µg
Cat # LS009002
20 µg, 100 µg
Human
$628
Cat # LS002151
20 µg, 100 µg
Cat # LS002151
20 µg, 100 µg
Human
$628
Cat # LS002149
20 µg, 100 µg
Cat # LS002149
20 µg, 100 µg
F2 Overview
Facts about Prothrombin.
Prothrombin (F2)
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | F2 |
| Uniprot: | P00734 |
| Entrez: | 2147 |
Family
| Belongs to: |
|---|
| peptidase S1 family |
Alternative Names
coagulation factor II (thrombin) receptor-like 2; Coagulation factor II receptor-like 2 (protease-actovated receptor 3); Coagulation factor II receptor-like 2; Coagulation Factor II; F2; PAR-3; PAR3proteinase-activated receptor 3; protease-activated receptor 3; proteinase-activated receptor-3; PT; serine protease; Thrombin receptor-like 2; Thrombin
Molecular Weight
Mass (kDA):
70.037 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p11.2 |
| Sequence: | 11; NC_000011.10 (46719201..46739506) |
Tissue Specificity
Expressed by the liver and secreted in plasma.
Subcellular Localizations
Secreted, extracellular space.
Diseases
- Hypertensive Disease
- Pathologic Vasoconstriction
- Neoplasms
- Fibrosis
- Observation Of Neuromuscular Block
- Liver Cirrhosis
- Hemorrhage
- Hepatitis
- Diabetes Mellitus
- Inflammation
- Plant Diseases
- Malignant Neoplasms
- Endometrial Polyp
Interacting Proteins
- THBD
Pathways
- Secretion
- Mating
- Luteolysis
- Ovulation
- Estrus
- Parturition
- Pathogenesis
- Excretion
- Vasoconstriction
- Transport
- Lactation
- Localization
- Vasodilation
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
- Oxidation
- Methylation
- Reduction
- Deglycosylation
- Nitration
- Hydroxylation
- Iodination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/F2
bosterbio.com/bosterbio-gene-info-cards/F2
References
PMID: 2825773 by Degen S.J.F., et al. Nucleotide sequence of the gene for human prothrombin.
PMID: 14962227 by Wang W., et al. Prothrombin Shanghai: hypoprothrombinaemia caused by substitution of Gla29 by Gly.
3 Publications of Boster Prothrombin Antibodies & ELISA Kits
- PubMed ID: 10.3389/fonc.2021.621806, Mining of RNA Methylation-Related Genes and Elucidation of Their Molecular Biolo...
- PubMed ID: 21642433, Heparin Impairs Angiogenesis through Inhibition of MicroRNA-10b
- PubMed ID: 27906434, D. QUANJUN, Z. QINGYU, Z. QILIANG, X. LIQUN, C. JINMEI, L. ZIQUAN, H. SHIKE Eur ...
*More publications can be found for each product on its corresponding product page