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- Table of Contents
Designing a Western blot for HMGB3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HMGB3 Western Blot Guide6 Citations
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Facts about High mobility group protein B3.
Associates with chromatin and binds DNA with a preference to non- canonical DNA structures like single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity).
| Human | |
|---|---|
| Gene Name: | HMGB3 |
| Uniprot: | O15347 |
| Entrez: | 3149 |

| Belongs to: |
|---|
| HMGB family |

High mobility group protein 2a; High mobility group protein 4; high mobility group protein B3; high-mobility group (nonhistone chromosomal) protein 4; high-mobility group box 3; HMG2A; HMG-2a; HMG2AHMG-4; HMG4; HMG4MGC90319; HMGB3; non-histone chromosomal protein
Mass (kDA):
22.98 kDA

| Human | |
|---|---|
| Location: | Xq28 |
| Sequence: | X; NC_000023.11 (150980507..150990775) |
Expressed predominantly in placenta.
Nucleus. Chromosome. Cytoplasm.






PMID: 9370291 by Wilke K., et al. Isolation of human and mouse HMG2a cDNAs: evidence for an HMG2a- specific 3' untranslated region.
PMID: 20598277 by Sun Y., et al. Terminal osseous dysplasia is caused by a single recurrent mutation in the FLNA gene.
*More publications can be found for each product on its corresponding product page