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- Table of Contents
23 Citations 9 Q&As
75 Citations 8 Q&As
47 Citations 12 Q&As
24 Citations 17 Q&As
1 Citations
Facts about Matrix metalloproteinase-9.
Cleaves KiSS1 at a Gly-.
| Human | |
|---|---|
| Gene Name: | MMP9 |
| Uniprot: | P14780 |
| Entrez: | 4318 |

| Belongs to: |
|---|
| peptidase M10A family |

92 kDa gelatinase; 92 kDa type IV collagenase; CLG4B; EC 3.4.24; EC 3.4.24.35; Gelatinase B; GELB; macrophage gelatinase; MANDP2; matrix metallopeptidase 9; matrix metalloproteinase 9; matrix metalloproteinase-9; MMP9; MMP-9; type V collagenase
Mass (kDA):
78.458 kDA

| Human | |
|---|---|
| Location: | 20q13.12 |
| Sequence: | 20; NC_000020.11 (46008908..46016561) |
Produced by normal alveolar macrophages and granulocytes.
Secreted, extracellular space, extracellular matrix.





PMID: 2551898 by Wilhelm S.M., et al. SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages.
PMID: 1653238 by Huhtala P., et al. Complete structure of the human gene for 92-kDa type IV collagenase. Divergent regulation of expression for the 92- and 72-kilodalton enzyme genes in HT-1080 cells.
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