This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
STAT1 Antibodies
AND STAT1 ELISA kits, STAT1 Proteins
Many biological assays use antibodies to detect STAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with STAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop STAT1 antibodies...
Designing a Western blot for STAT1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the STAT1 Western Blot GuideSTAT1 Infographic by Boster Bio
All STAT1 Products
Product
Figures
Specificity
Applications
Price
Anti-CD44 Picoband® Antibody (monoclonal, 7H7)
17 Citations
Human, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M00052-3
100 μg/vial
Cat # M00052-3
100 μg/vial
Anti-STAT1 Antibody Picoband® (monoclonal, 12C7)
4 Citations
Human, Monkey
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00036-2
100 μg/vial
Cat # M00036-2
100 μg/vial
Anti-STAT1 Rabbit Monoclonal Antibody
2 Citations
Human, Mouse
Flow Cytometry, IP, IHC, WB
$370
Cat # M00036-1
100 μl
Cat # M00036-1
100 μl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00043-1
100 μg/vial
Cat # M00043-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M00043
100 μg/vial
Cat # M00043
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00036-2
100 μg/vial
Cat # A00036-2
100 μg/vial
Human
IHC, WB
$370
Cat # M00044-2
100 μg/vial
Cat # M00044-2
100 μg/vial
Anti-STAT1 Antibody Picoband®
2 Citations
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # PB9510
100 μg/vial
Cat # PB9510
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # PA1075
100 μg/vial
Cat # PA1075
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # M00044-3
100 μg/vial
Cat # M00044-3
100 μg/vial
Anti-STAT1 alpha Rabbit Monoclonal Antibody
1 Citations
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00036
100 μl
Cat # M00036
100 μl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00036-6
20μL, 40μL, 100μL, 200μL
Cat # M00036-6
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA
$540
Cat # EKC2514
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2514
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2513
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2513
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1541
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1541
1 kit, containing one 96-well plate and all necessary reagents
Functional Assay
$5040
Cat # RC1013
1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
Cat # RC1013
1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
Functional Assay
$5040
Cat # RC1012
1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
Cat # RC1012
1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
STAT1 Overview
Facts about Signal transducer and activator of transcription 1-alpha/beta.
Signal transducer and activator of transcription 1-alpha/beta (STAT1)
Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. After type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases contributes to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2.
The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus (PubMed:28753426). ISGF3 binds to the IFN stimulated response element (ISRE) to trigger the transcription of IFN-stimulated genes (ISG), which drive the mobile in an antiviral state.
Gene Information
| Human | |
|---|---|
| Gene Name: | STAT1 |
| Uniprot: | P42224 |
| Entrez: | 6772 |
Family
| Belongs to: |
|---|
| transcription factor STAT family |
Alternative Names
CANDF7; DKFZp686B04100; ISGF-3; ISGF-3,91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription-1; STAT1; STAT91
Molecular Weight
Mass (kDA):
87.335 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q32.2 |
| Sequence: | 2; NC_000002.12 (190968989..191014250, complement) |
Subcellular Localizations
Cytoplasm. Nucleus. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to IFN-gamma and signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4 (PubMed:15322115). Monomethylation at Lys-525 is required for phosphorylation at Tyr-701 and translocation into the nucleus (PubMed:28753426). Translocates into the nucleus in response to interferon-beta stimulation (PubMed:26479788).
Diseases
- Neoplasms
- Malignant Neoplasms
- Inflammation
- Janiceps
- Virus Diseases
- Leukemia
- Carcinoma
- Infective Disorder
- Hepatitis
- Cell Transformation, Neoplastic
- Autoimmune Reaction
- Tissue Adhesions
- Liver Carcinoma
Interacting Proteins
- DDB1
- DDX58
- E2F1
- EGFR
- EIF1AD
- ERBB2
- FOS
- IFNAR1
- IFNAR2
- IFNGR1
Pathways
- Pathogenesis
- Immune Response
- Cell Proliferation
- Secretion
- Cell Growth
- Cell Death
- Localization
- Cell Cycle
- Inflammatory Response
- Cell Differentiation
- Cytokine Production
- Viral Replication
- Cell Activation
PTMs
- Phosphorylation
- Dephosphorylation
- Methylation
- Cleavage
- Acetylation
- Ubiquitination
- Sumoylation
- Nitration
- Reduction
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STAT1
bosterbio.com/bosterbio-gene-info-cards/STAT1
References
PMID: 1502203 by Schindler C., et al. Proteins of transcription factor ISGF-3: one gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon alpha.
PMID: 7885841 by Yan R., et al. The genomic structure of the STAT genes: multiple exons in coincident sites in Stat1 and Stat2.
25 Publications of Boster STAT1 Antibodies & ELISA Kits
- PubMed ID: 10.3748/wjg.v13.i32.4360, Effects of body-resistance strengthening and tumor-suppressing granules on immun...
- PubMed ID: 10.3748/wjg.v13.i30.4080, Hepatitis C Virus non-structural 5A abrogates signal transducer and activator of...
- PubMed ID: 10.3390/molecules23010223, Protective Mechanism of the Antioxidant Baicalein toward Hydroxyl Radical-Treate...
- PubMed ID: 10.3390/molecules23010222, Antioxidant and Cytoprotective Effects of the Di-O-Caffeoylquinic Acid Family: T...
- PubMed ID: 10.3390/ijms18030570, Blockage of Glyoxalase I Inhibits Colorectal Tumorigenesis and Tumor Growth via ...
- PubMed ID: 10.1620/tjem.233.175, Colorectal Cancer Progression Is Associated with Accumulation of Th17 Lymphocyte...
- PubMed ID: 10.1186/s13065-017-0313-1, Two phenolic antioxidants in Suoyang enhance viability of •OH-damaged mesenchy...
- PubMed ID: 10.1186/1471-2407-8-135, Suspension culture combined with chemotherapeutic agents for sorting of breast c...
- PubMed ID: 10.1016/j.joca.2007.09.002, Articular cartilage metabolism in patients with Kashin–Beck Disease: an endemi...
- PubMed ID: 10.1016/j.arabjc.2017.03.008, Effect and mechanism of wedelolactone as antioxidant-coumestan on OH-treated mes...
- PubMed ID: 10.1007/s12013-014-0222-z, Differentiation of Mesenchymal Stem Cells into Neural Stem Cells Using Cerebrosp...
- PubMed ID: 10.1007/s00467-009-1163-4, Expression of JAKs/STATs pathway molecules in rat model of rapid focal segmental...
- PubMed ID: 10.1007/s00432-008-0391-5, Prognostic significance of Survivin and CD44v6 in laryngeal cancer surgical marg...
- PubMed ID: 10.1007/s00403-008-0872-z, Effects of acitretin on proliferative inhibition and RANTES production of HaCaT ...
- PubMed ID: 10.1002/cbf.1523, Inhibitory effect of mesenchymal stem cells on lymphocyte proliferation
- PubMed ID: , Death signal transduction induced by co-immobilized TNF-α plus IFN-γ and the d...
- PubMed ID: 32204409, Kubatka P,Kello M,Kajo K,Samec M,Jasek K,Vybohova D,Uramova S,Liskova A,Sadlonov...
- PubMed ID: -, Wu,H.,Jiang,X.,Li,Y.,Zhou,Y.,Zhang,T.,Zhi,P.,Gao,J.,Engineering Stem Cell Derive...
- PubMed ID: 32869841, Zhang GF,Wu JC,Wang HY,Jiang WD,Qiu L. Overexpression of microRNA-205-5p exerts ...
- PubMed ID: 33375383, Kubatka P,Kello M,Kajo K,Samec M,Liskova A,Jasek K,Koklesova L,Kuruc T,Adamkov M...
- PubMed ID: 31731208, Gao Y,Gui F,Li D,Zhang R,Sun Q,Guo X.Fluoride regulates the expression of extrac...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page