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- Table of Contents
TNFRSF1A Antibodies
AND TNFRSF1A ELISA kits, TNFRSF1A Proteins
Many biological assays use antibodies to detect TNFRSF1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNFRSF1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNFRSF1A antibodies...
Designing a Western blot for TNFRSF1A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TNFRSF1A Western Blot GuideTNFRSF1A Infographic by Boster Bio
All TNFRSF1A Products
Product
Figures
Specificity
Applications
Price
Human TNFsR I ELISA Kit PicoKine®
3 Citations
Human
ELISA
$499
Cat # EK0528
96 wells/kit, with removable strips.
Cat # EK0528
96 wells/kit, with removable strips.
Anti-TNF Receptor I/TNFRSF1A Antibody Picoband®
5 Citations
Human, Mouse, Rat
IHC, WB, ELISA (Cap)
$370
Cat # A00294-3
100 μg/vial
Cat # A00294-3
100 μg/vial
Mouse TNFsR I ELISA Kit PicoKine®
2 Citations
Mouse
ELISA
$499
Cat # EK0529
96 wells/kit, with removable strips.
Cat # EK0529
96 wells/kit, with removable strips.
Anti-TNFRSF1A Antibody Picoband®
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # A00294
100 μg/vial
Cat # A00294
100 μg/vial
Mouse
ELISA
$750
Cat # EK2008
96 wells/kit, with removable strips.
Cat # EK2008
96 wells/kit, with removable strips.
Mouse
ELISA
$750
Cat # EK2007
96 wells/kit, with removable strips.
Cat # EK2007
96 wells/kit, with removable strips.
TNFRSF1A Overview
Facts about Tumor necrosis factor receptor superfamily member 1A.
Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A)
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha.
The adapter molecule FADD recruits caspase-8 to the activated receptor.The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate- specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Gene Information
| Human | |
|---|---|
| Gene Name: | TNFRSF1A |
| Uniprot: | P19438 |
| Entrez: | 7132 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD120a antigen; CD120a; FPF; p55; p55-R; p60; TNF RI; TNFARMGC19588; TNF-R; TNF-R1; TNFR1TBP1; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRSF1A; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; Tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor
Molecular Weight
Mass (kDA):
50.495 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12p13.31 |
| Sequence: | 12; NC_000012.12 (6328771..6342076, complement) |
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Secreted. A secreted form is produced through proteolytic processing.; [Isoform 4]: Secreted. Lacks a Golgi-retention motif, is not membrane bound and therefore is secreted.
Diseases
- Inflammation
- Familial Mediterranean Fever
- Tnf Receptor-associated Periodic Fever Syndrome (traps)
- Pain
- Arthritis
- Hereditary Autoinflammatory Diseases
- Brucellosis
- Inflammatory Response
- Exanthema
- Abdominal Pain
- Amyloidosis
- Malignant Neoplasms
Interacting Proteins
- GRN
- RFK
- RIPK1
- TNF
- TRADD
- TRAF2
Pathways
- Pathogenesis
- Cell Death
- Inflammatory Response
- Immune Response
- Secretion
- Cell Proliferation
- Angiogenesis
- Cytokine Production
- Cell Activation
- Regeneration
- Hypersensitivity
- Sensitization
- Innate Immune Response
PTMs
- Phosphorylation
- Cleavage
- Glycosylation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNFRSF1A
bosterbio.com/bosterbio-gene-info-cards/TNFRSF1A
References
PMID: 2158862 by Loetscher H., et al. Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor.
PMID: 2158863 by Schall T.J., et al. Molecular cloning and expression of a receptor for human tumor necrosis factor.
13 Publications of Boster TNFRSF1A Antibodies & ELISA Kits
- PubMed ID: 10.3390/ijms10052010, Soluble Tumor Necrosis Factor Receptor Mediates Cell Proliferation on Lipopolysa...
- PubMed ID: 10.1039/C5TB00514K, Design of magnetic nanoparticles for hepatocellular carcinoma treatment using th...
- PubMed ID: 10.1038/bmt.2017.121, Endothelial damage is aggravated in acute GvHD and could predict its development
- PubMed ID: 10.1016/j.toxicon.2007.07.020, Effect of Huwentoxin-I on the Fas and TNF apoptosis pathway in the hippocampus o...
- PubMed ID: 10.1016/j.jep.2021.114063, Antiviral effect of fufang yinhua jiedu (FFYH) granules against influenza A viru...
- PubMed ID: 10.1016/j.bbrc.2017.11.009, DT-13 ameliorates TNF-α-induced nitric oxide production in the endothelium in ...
- PubMed ID: -, Zhiwei Liao,Suyun Li,Rong Liu,Xiaobo Feng,Yunsong Shi,Kun Wang,Shuai Li,Yukun Zh...
- PubMed ID: -, Determination Levels of Tumor Necrosis Factor Receptor and Tolk like Receptor-4 ...
- PubMed ID: 33813013, Zhang Y,Wang R,Shi W,Zhihui Z,Wang X,Li C,Zhang S,Zhang P. Antiviral effect of f...
- PubMed ID: 27275821, Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therap...
- PubMed ID: 19564935, Soluble Tumor Necrosis Factor Receptor Mediates Cell Proliferation on Lipopolysa...
- PubMed ID: 25267210, TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integratin...
- PubMed ID: 24845203, Powerful inner/outer controlled multi-target magnetic nanoparticle drug carrier ...
*More publications can be found for each product on its corresponding product page