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- Table of Contents
Designing a Western blot for CD40? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CD40 Western Blot Guide1 Citations
1 Citations
5 Citations
1 Citations
Facts about Tumor necrosis factor receptor superfamily member 5.
Receptor for TNFSF5/CD40LG.
Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, resulting in induction of immunoglobulin secretion..
| Human | |
|---|---|
| Gene Name: | CD40 |
| Uniprot: | P25942 |
| Entrez: | 958 |

| Belongs to: |
|---|
| No superfamily |

B cell surface antigen CD40; B-cell surface antigen CD40; Bp50B cell-associated molecule; CD40 antigen; CD40 molecule, TNF receptor superfamily member 5; CD40 type II isoform; CD40; CD40L receptor; CDw40; MGC9013; nerve growth factor receptor-related B-lymphocyte activation molecule; p50; TNFRSF5; TNFRSF5CD40 antigen (TNF receptor superfamily member 5); tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5
Mass (kDA):
30.619 kDA

| Human | |
|---|---|
| Location: | 20q13.12 |
| Sequence: | 20; NC_000020.11 (46118242..46129858) |
B-cells and in primary carcinomas.
[Isoform I]: Cell membrane; Single-pass type I membrane protein.; [Isoform II]: Secreted.






PMID: 2475341 by Stamenkovic I., et al. A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.
PMID: 11172023 by Tone M., et al. Regulation of CD40 function by its isoforms generated through alternative splicing.
*More publications can be found for each product on its corresponding product page