Coagulation factor XI Antibodies

AND F11 ELISA kits, Coagulation factor XI Proteins

Many biological assays use antibodies to detect Coagulation factor XI, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Coagulation factor XI in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Coagulation factor XI antibodies...

We validate the specificity of these antibodies to Coagulation factor XI by testing them on tissues known to express F11 positively and negatively. Browse below to find the F11 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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F11 Infographic by Boster Bio

All F11 Products

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Factor XI (F11) (NM_000128) Human Recombinant Protein

Coomassie blue staining of purified F11 protein

$1249
Cat # PROTP03951
20 µg

Anti-FXI/F11 Antibody Picoband®

Western blot analysis of FXI/F11 using anti-FXI/F11 antibody (A00989-1)

IF analysis of FXI/F11 using anti-FXI/F11 antibody (A00989-1)

Flow Cytometry analysis of HepG2 cells using anti-FXI/F11 antibody (A00989-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A00989-1
100 μg/vial

Human F11 ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK2199
96 wells/kit, with removable strips.

Factor XI (F11) (NM_000128) Human Over-expression Lysate

Human

$960
Cat # LS002160
20 µg, 100 µg

Anti-F11 / Factor XI Reference Antibody (abelacimab)

The purity of Anti-F11/Factor XI Reference Antibody (abelacimab)is more than 95%

Human

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M00989
100 μg

Anti-F11 / Factor XI Reference Antibody (osocimab)

The purity of Anti-F11/Factor XI Reference Antibody (osocimab)is more than 95%

Human, Rabbit

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M00989-1
100 μg

F11 Overview

Facts about Coagulation factor XI.

F11 3D structure. Source: alphafold

Coagulation factor XI (F11)

Factor XI triggers the middle stage of the intrinsic pathway of blood coagulation by activating factor IX. .

Gene Information

Human
Gene Name:	F11
Uniprot:	P03951
Entrez:	2160

Family

Belongs to:

peptidase S1 family

Alternative Names

Coagulation Factor XI; EC 3.4.21; EC 3.4.21.27; FXIPlasma thromboplastin antecedent; MGC141891; PTA

Molecular Weight

Mass (kDA):
70.109 kDA

Genomic Context


Human

Location:	4q35.2
Sequence:	4; NC_000004.12 (186265964..186290727)

Tissue Specificity

Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells.

Subcellular Localizations

Secreted.

Diseases

Tissue Adhesions
Factor Xi Deficiency
Escherichia Coli Infections
Hemorrhage
Nervousness
Malignant Neoplasms
Neoplasms
Infective Disorder
Neuroblastoma
Urinary Tract Infection
Muscular Fasciculation
Bleeding Tendency
Thrombosis

Poultry Diseases
Tuberculosis
Pain
Cholera
Venous Thrombosis
Pertussis
Malignant Neoplasm Of Prostate

Pathways

Cell Adhesion
Coagulation
Localization
Virulence
Pathogenesis
Secretion
Regeneration
Cell Death
Glycosylation
Neurogenesis
Cell Recognition
Platelet Aggregation
Blood Coagulation

Bone Resorption
Cell Proliferation
Drug Resistance
Gametophytic Self-incompatibility
Transposition
Cell Migration
Fermentation

PTMs

Phosphorylation
Glycosylation
Cleavage
Deglycosylation

Carboxylation
Hydroxylation
Dephosphorylation
Acylation

Gpi Anchoring

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/F11

References

PMID: 3636155 by Fujikawa K., et al. Amino acid sequence of human factor XI, a blood coagulation factor with four tandem repeats that are highly homologous with plasma prekallikrein.

PMID: 2827746 by Asakai R., et al. Organization of the gene for human factor XI.