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- Table of Contents
Complement C2 Antibodies
AND C2 ELISA kits, Complement C2 Proteins
Many biological assays use antibodies to detect Complement C2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Complement C2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Complement C2 antibodies...
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C2 Infographic by Boster Bio
All C2 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK2143
96 wells/kit, with removable strips.
Cat # EK2143
96 wells/kit, with removable strips.
Cynomolgus monkey, Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00573-1
100 μg
Cat # M00573-1
100 μg
C2 Overview
Facts about Complement C2.
Complement C2 (C2)
Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | C2 |
| Uniprot: | P06681 |
| Entrez: | 717 |
Family
| Belongs to: |
|---|
| peptidase S1 family |
Alternative Names
Complement Component C2b
Molecular Weight
Mass (kDA):
83.268 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p21.33 |
| Sequence: | 6; NC_000006.12 (31897783..31945674) |
Subcellular Localizations
Secreted.
Diseases
- Neoplasms
- Fracture
- Pain
- Malignant Neoplasms
- Carcinoma
- Dislocations
- Infective Disorder
- Spinal Fractures
- Spinal Cord Injuries
- Neck Pain
- Hiv Infections
- Disease Of Adrenal Medulla
- Hemorrhage
Pathways
- Transport
- Localization
- Pathogenesis
- Secretion
- Complement Activation
- Coagulation
- Translation
- Reflex
- Cell Death
- Proteolysis
- Cell Cycle
- Immune Response
- Cell Proliferation
PTMs
- Cleavage
- Phosphorylation
- Oxidation
- Ribosylation
- Glycosylation
- Methylation
- Reduction
- Carboxylation
- Hydroxylation
- Nitration
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/C2
bosterbio.com/bosterbio-gene-info-cards/C2
References
PMID: 2949737 by Bentley D.R.; Primary structure of human complement component C2. Homology to two unrelated protein families.
PMID: 2493504 by Horiuchi T., et al. cDNA cloning and expression of human complement component C2.