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- Table of Contents
GDNF Antibodies
AND GDNF ELISA kits, GDNF Proteins
Many biological assays use antibodies to detect GDNF, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GDNF in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GDNF antibodies...
Designing a Western blot for GDNF? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GDNF Western Blot GuideGDNF Infographic by Boster Bio
All GDNF Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0362
96 wells/kit, with removable strips.
Cat # EK0362
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0470
96 wells/kit, with removable strips.
Cat # EK0470
96 wells/kit, with removable strips.
Mouse GDNF ELISA Kit PicoKine®
7 Citations
Mouse
ELISA
$399
Cat # EK0935
96 wells/kit, with removable strips.
Cat # EK0935
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ0362
5 plates/kit
Cat # EZ0362
5 plates/kit
Human
ELISA
$499
Cat # FEK0362
96 wells/kit, with removable strips.
Cat # FEK0362
96 wells/kit, with removable strips.
Human
IHC, WB
$370
Cat # PB9202
100 μg/vial
Cat # PB9202
100 μg/vial
Human
Cell Culture
$77
Cat # PROTP39905-3
5ug,20ug,100ug
Cat # PROTP39905-3
5ug,20ug,100ug
Mouse
Cell Culture
$77
Cat # PROTP48540-2
5ug,20ug,100ug
Cat # PROTP48540-2
5ug,20ug,100ug
Human
$960
Cat # LS002674
20 µg, 100 µg
Cat # LS002674
20 µg, 100 µg
Human
$628
Cat # LS002675
20 µg, 100 µg
Cat # LS002675
20 µg, 100 µg
GDNF Overview
Facts about Glial cell line-derived neurotrophic factor.
Glial cell line-derived neurotrophic factor (GDNF)
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. .
Gene Information
| Human | |
|---|---|
| Gene Name: | GDNF |
| Uniprot: | P39905 |
| Entrez: | 2668 |
Family
| Belongs to: |
|---|
| TGF-beta family |
Alternative Names
Astrocyte-derived trophic factor; ATF; ATF1; ATF2; GDNF; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; glial cell line-derived neurotrophic factor; HFB1-GDNF; HGDNF; HSCR3
Molecular Weight
Mass (kDA):
23.72 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5p13.2 |
| Sequence: | 5; NC_000005.10 (37812677..37840044, complement) |
Tissue Specificity
In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.
Subcellular Localizations
Secreted.
Diseases
- Parkinson Disease
- Nervousness
- Neurodegenerative Disorders
- Nerve Degeneration
- Secondary Parkinson Disease
- Neoplasms
- Hirschsprung Disease
- Ischemia
- Pain
- Spinal Cord Injuries
- Inflammation
- Nerve Damage
- Sclerosis
Interacting Proteins
- AGTRAP
Pathways
- Regeneration
- Cell Death
- Neuroprotection
- Innervation
- Secretion
- Pathogenesis
- Cell Proliferation
- Kidney Development
- Transport
- Spermatogenesis
- Localization
- Cell Adhesion
- Neurogenesis
PTMs
- Phosphorylation
- Reduction
- Cleavage
- Glycosylation
- Methylation
- Acetylation
- Ubiquitination
- Iodination
- Biotinylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GDNF
bosterbio.com/bosterbio-gene-info-cards/GDNF
References
PMID: 8493557 by Lin L.-F.H., et al. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons.
PMID: 7867768 by Schaar D.G., et al. Multiple astrocyte transcripts encode nigral trophic factors in rat and human.
86 Publications of Boster GDNF Antibodies & ELISA Kits
- PubMed ID: 10.5483/BMBRep.2018.51.11.123, 3-(Naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride attenuates MPP+-induce...
- PubMed ID: 10.4142/jvs.2016.17.1.97, Expression of neurotrophic factors in injured spinal cord after transplantation ...
- PubMed ID: 10.4103/1673-5374.286977, A novel tissue engineered nerve graft constructed with autologous vein and nerve...
- PubMed ID: 10.3969/j.issn.1673-5374.2013.23.009, Antenatal taurine reduces cerebral cell apoptosis in fetal rats with intrauterin...
- PubMed ID: 10.3390/ijms22020781, Macrophage-Derived Inflammation Induces a Transcriptome Makeover in Mesenchymal ...
- PubMed ID: 10.3389/fnagi.2020.590530, Long-Term Running Exercise Delays Age-Related Changes in White Matter in Rats
- PubMed ID: 10.3233/RNN-150607, Granulocyte-colony stimulating factor promotes brain repair following traumatic ...
- PubMed ID: 10.24272/j.issn.2095-8137.2020.186, Dmrt1 regulates the immune response by repressing the TLR4 signaling pathway in ...
- PubMed ID: 10.2147/TCRM.S182325, The expressions of NGF and VEGF in the fracture tissues are closely associated w...
- PubMed ID: 10.18632/oncotarget.12720, Melatonin promotes goat spermatogonia stem cells (SSCs) proliferation by stimula...
- PubMed ID: 10.18632/aging.202460, Triptolide improves neurobehavioral functions, inflammation, and oxidative stres...
- PubMed ID: 10.1186/s12871-018-0491-y, The interplay of BDNF-TrkB with NMDA receptor in propofol-induced cognition dysf...
- PubMed ID: 10.1186/1479-5876-8-77, Modulation of the major histocompatibility complex by neural stem cell-derived n...
- PubMed ID: 10.1155/2014/267808, The Role of Neurotrophic Factors Conjugated to Iron Oxide Nanoparticles in Perip...
- PubMed ID: 10.1126/sciadv.abi5812, Bionic microenvironment-inspired synergistic effect of anisotropic micro-nanocom...
- PubMed ID: 10.1111/jcmm.14756, Low‐level laser therapy 810‐nm up‐regulates macrophage secretion of neurot...
- PubMed ID: 10.1111/and.14056, Culture bovine prospermatogonia with 2i medium
- PubMed ID: 10.1089/rej.2015.1751, Effect of Zhuang Jing Decoction on Learning and Memory Ability in Aging Rats
- PubMed ID: 10.1080/24750573.2017.1415186, Serum glial cell line-derived neurotrophic factor levels and impulsivity in hero...
- PubMed ID: 10.1038/s41598-021-87814-7, Transitional changes in gastrointestinal transit and rectal sensitivity from act...
- PubMed ID: 10.1021/acschemneuro.5b00189, Magnetic NGF-Releasing PLLA/Iron Oxide Nanoparticles Direct Extending Neurites a...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page