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- Table of Contents
GDNF Antibodies
AND GDNF ELISA kits, GDNF Proteins
Many biological assays use antibodies to detect GDNF, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GDNF in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GDNF antibodies...
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GDNF Infographic by Boster Bio
All GDNF Products
Product
Figures
Specificity
Applications
Price
Human GDNF / Glial Derived Neurotrophic Factor ELISA Kit PicoKine®
19 Citations 10 Q&As
Human
ELISA
$499
Cat # EK0362
96 wells/kit, with removable strips.
Cat # EK0362
96 wells/kit, with removable strips.
Rat GDNF ELISA Kit PicoKine®
24 Citations 11 Q&As
Rat
ELISA
$499
Cat # EK0363
96 wells/kit, with removable strips.
Cat # EK0363
96 wells/kit, with removable strips.
Mouse GDNF ELISA Kit PicoKine®
7 Citations 6 Q&As
Mouse
ELISA
$399
Cat # EK0935
96 wells/kit, with removable strips.
Cat # EK0935
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK0362
96 wells/kit, with removable strips.
Cat # FEK0362
96 wells/kit, with removable strips.
Rat
ELISA
$499
Cat # FEK0363
96 wells/kit, with removable strips.
Cat # FEK0363
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # FEK0935
96 wells/kit, with removable strips.
Cat # FEK0935
96 wells/kit, with removable strips.
Human
Cell Culture
$77
Cat # PROTP39905-3
5ug,20ug,100ug
Cat # PROTP39905-3
5ug,20ug,100ug
Mouse
Cell Culture
$77
Cat # PROTP48540-2
5ug,20ug,100ug
Cat # PROTP48540-2
5ug,20ug,100ug
Human
ELISA
$500
Cat # EZ0362
5 plates/kit
Cat # EZ0362
5 plates/kit
GDNF Overview
Facts about Glial cell line-derived neurotrophic factor.
Glial cell line-derived neurotrophic factor (GDNF)
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. .
Gene Information
| Human | |
|---|---|
| Gene Name: | GDNF |
| Uniprot: | P39905 |
| Entrez: | 2668 |
Family
| Belongs to: |
|---|
| TGF-beta family |
Alternative Names
Astrocyte-derived trophic factor; ATF; ATF1; ATF2; GDNF; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; glial cell line-derived neurotrophic factor; HFB1-GDNF; HGDNF; HSCR3
Molecular Weight
Mass (kDA):
23.72 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5p13.2 |
| Sequence: | 5; NC_000005.10 (37812677..37840044, complement) |
Tissue Specificity
In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.
Subcellular Localizations
Secreted.
Diseases
- Parkinson Disease
- Nervousness
- Neurodegenerative Disorders
- Nerve Degeneration
- Secondary Parkinson Disease
- Neoplasms
- Hirschsprung Disease
- Ischemia
- Pain
- Spinal Cord Injuries
- Inflammation
- Nerve Damage
- Sclerosis
Interacting Proteins
- AGTRAP
Pathways
- Regeneration
- Cell Death
- Neuroprotection
- Innervation
- Secretion
- Pathogenesis
- Cell Proliferation
- Kidney Development
- Transport
- Spermatogenesis
- Localization
- Cell Adhesion
- Neurogenesis
PTMs
- Phosphorylation
- Reduction
- Cleavage
- Glycosylation
- Methylation
- Acetylation
- Ubiquitination
- Iodination
- Biotinylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GDNF
bosterbio.com/bosterbio-gene-info-cards/GDNF
References
PMID: 8493557 by Lin L.-F.H., et al. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons.
PMID: 7867768 by Schaar D.G., et al. Multiple astrocyte transcripts encode nigral trophic factors in rat and human.
42 Publications of Boster GDNF Antibodies & ELISA Kits
- PubMed ID: 10.5483/BMBRep.2018.51.11.123, 3-(Naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride attenuates MPP+-induce...
- PubMed ID: 10.3969/j.issn.1673-5374.2013.23.009, Antenatal taurine reduces cerebral cell apoptosis in fetal rats with intrauterin...
- PubMed ID: 10.3390/ijms22020781, Macrophage-Derived Inflammation Induces a Transcriptome Makeover in Mesenchymal ...
- PubMed ID: 10.3233/RNN-150607, Granulocyte-colony stimulating factor promotes brain repair following traumatic ...
- PubMed ID: 10.24272/j.issn.2095-8137.2020.186, Dmrt1 regulates the immune response by repressing the TLR4 signaling pathway in ...
- PubMed ID: 10.18632/oncotarget.12720, Melatonin promotes goat spermatogonia stem cells (SSCs) proliferation by stimula...
- PubMed ID: 10.1186/s12871-018-0491-y, The interplay of BDNF-TrkB with NMDA receptor in propofol-induced cognition dysf...
- PubMed ID: 10.1155/2014/267808, The Role of Neurotrophic Factors Conjugated to Iron Oxide Nanoparticles in Perip...
- PubMed ID: 10.1126/sciadv.abi5812, Bionic microenvironment-inspired synergistic effect of anisotropic micro-nanocom...
- PubMed ID: 10.1111/and.14056, Culture bovine prospermatogonia with 2i medium
- PubMed ID: 10.1080/24750573.2017.1415186, Serum glial cell line-derived neurotrophic factor levels and impulsivity in hero...
- PubMed ID: 10.1016/j.msard.2020.102143, Exercise improves neurotrophins in multiple sclerosis independent of disability ...
- PubMed ID: 10.1016/j.jpsychires.2020.04.009, A synergistic effect between family intervention and rTMS improves cognitive and...
- PubMed ID: 10.1016/j.expneurol.2014.05.019, Spatiotemporally limited BDNF and GDNF overexpression rescues motoneurons destin...
- PubMed ID: 10.1016/j.bios.2021.113179, On chip detection of glial cell-derived neurotrophic factor secreted from dopami...
- PubMed ID: 10.1007/s12031-016-0856-y, GPR30 Activation Contributes to the Puerarin-Mediated Neuroprotection in MPP+-In...
- PubMed ID: 10.1007/s00787-016-0898-2, Serum brain-derived neurotrophic factor, glial-derived neurotrophic factor, nerv...
- PubMed ID: 10.1007/s00702-018-1949-2, Neurogenesis within the hippocampus after chronic methylphenidate exposure
- PubMed ID: 10.1002/mus.26862, Magnetic resonance imaging of enhanced nerve repair with mesenchymal stem cells ...
- PubMed ID: 10.1002/jnr.23714, Granulocyte colony‐stimulating factor promotes behavioral recovery in a mouse ...
- PubMed ID: 10.1002/jcp.26920, H19 regulates the proliferation of bovine male germline stem cells via IGF‐1 s...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page