Many biological assays use antibodies to detect HLA-C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HLA-C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HLA-C antibodies...
We validate the specificity of these antibodies to HLA-C by testing them on tissues known to express HLA-C positively and negatively. Browse below to find the HLA-C antibody that suites your experiment. We have 50 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
Facts about HLA class I histocompatibility antigen, C alpha chain.
HLA class I histocompatibility antigen, C alpha chain (HLA-C)
Involved in the presentation of foreign antigens to the immune system. .
Gene Information
Human
Gene Name:
HLA-C
Uniprot:
P04222
Entrez:
3107
Family
Belongs to:
No superfamily
Alternative Names
C alpha chain; D6S204; FLJ27082; HLA class I histocompatibility antigen, Cw-1 alpha chain; HLAC; HLA-C; HLA-Cw; HLA-JY3; HLC-C; human leukocyte antigen-C alpha chain; leucocyte antigen C; leucocyte antigen Cw; leukocyte antigen-C alpha chain; major histocompatibility antigen HLA-C; major histocompatibility complex, class I, C; MHC class I antigen Cw*1; MHC class I antigen Cw*12; MHC class I antigen Cw*14; MHC class I antigen Cw*15; MHC class I antigen Cw*16; MHC class I antigen Cw*17; MHC class I antigen Cw*2; MHC class I antigen Cw*3; MHC class I antigen Cw*4; MHC class I antigen Cw*5; MHC cl
Molecular Weight
Mass (kDA): 40.649 kDA
Genomic Context
Human
Location:
6p21.33
Sequence:
6; NC_000006.12 (31268749..31272092, complement)
Diseases
Psoriasis
Dysequilibrium Syndrome
Neoplasms
Hiv Infections
Malignant Neoplasms
Arthritis
Leukemia
Graft-vs-host Disease
Autoimmune Reaction
Arthritis, Psoriatic
Carcinoma
Autoimmune Diseases
Immunologic Deficiency Syndromes
Diabetes Mellitus
Infective Disorder
Hepatitis
Virus Diseases
Diabetes Mellitus, Insulin-dependent
Hepatitis C
Pathways
Pathogenesis
Immune Response
Cell Activation
Gene Conversion
Cell Recognition
Localization
Transport
Secretion
Cytolysis
Donor Selection
Methylation
Cytokine Production
Glycosylation
T Cell Activation
Translation
Cell Proliferation
Sensitization
Cell Killing
Inflammatory Response
Viral Replication
PTMs
Phosphorylation
Glycosylation
Methylation
Cleavage
Dephosphorylation
Iodination
Biotinylation
Palmitoylation
Deglycosylation
Ubiquitination
Research Areas
Adaptive Immunity
Immunology
For details, visit: bosterbio.com/bosterbio-gene-info-cards/HLA-C
References
PMID: 2914713 by Cianetti L., et al. Three new class I HLA alleles: structure of mRNAs and alternative mechanisms of processing.
PMID: 1711567 by Grassi F., et al. Human immunodeficiency virus type 1 gp120 mimics a hidden monomorphic epitope borne by class I major histocompatibility complex heavy chains.
6 Publications of Boster HLA-C Antibodies & ELISA Kits
PubMed ID: 10.1371/journal.pone.0258817, PKI-587 enhances radiosensitization of hepatocellular carcinoma by inhibiting th...
PubMed ID: 10.1007/s10495-017-1391-1, Multi-targeted therapy of everolimus in Kaposi’s sarcoma associated herpes vir...
PubMed ID: , Performance of a multilayered small-diameter vascular scaffold dual-loaded with ...
PubMed ID: , IFN-γ enhances cell-mediated cytotoxicity against keratinocytes via JAK2/STAT1 ...