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- Table of Contents
Phosducin Antibodies
AND PDC ELISA kits, Phosducin Proteins
Many biological assays use antibodies to detect Phosducin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Phosducin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Phosducin antibodies...
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PDC Overview
Facts about Phosducin.
Phosducin (PDC)
May participate in the regulation of visual phototransduction or at the integration of photoreceptor metabolism. Inhibits the transcriptional activation activity of this cone-rod homeobox CRX.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | PDC |
| Uniprot: | P20941 |
| Entrez: | 5132 |
Family
| Belongs to: |
|---|
| phosducin family |
Alternative Names
33 kDa phototransducing protein; 33kDA phototransducing protein; G beta gamma binding protein; PHD; PhLP; phosducin; phosducin-like orphan protein
Molecular Weight
Mass (kDA):
28.246 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q31.1 |
| Sequence: | 1; NC_000001.11 (186443566..186461114, complement) |
Subcellular Localizations
Cytoplasm, cytosol. Nucleus. Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment.; [Isoform 2]: Nucleus.
Diseases
- Dementia
- Amyotrophic Lateral Sclerosis
- Liver Cirrhosis
- Primary Biliary Cirrhosis
- Biliary Cirrhosis
- Secondary Parkinson Disease
- Neoplasms
- Autoimmune Reaction
- Neurodegenerative Disorders
- Parkinson Disease
- Sclerosis
- Malignant Neoplasms
- Primary Lateral Sclerosis
Pathways
- Fermentation
- Transport
- Pathogenesis
- Secretion
- Immune Response
- Glycolysis
- Cell Death
- Sensitization
- Endocytosis
- Cell Proliferation
- Aging
- Localization
- Cytokine Production
PTMs
- Phosphorylation
- Oxidation
- Decarboxylation
- Dephosphorylation
- Acetylation
- Carboxylation
- Methylation
- Cleavage
- Reduction
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDC
bosterbio.com/bosterbio-gene-info-cards/PDC
References
PMID: 2210381 by Abe T., et al. Analysis of the human, bovine and rat 33-kDa proteins and cDNA in retina and pineal gland.
PMID: 2383274 by Watanabe Y., et al. Isolation and analysis of the human MEKA gene encoding a retina- specific protein.