- Table of Content
Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion.
|tetraspanin (TM4SF) family|
|Sequence:||12; NC_000012.12 (6199946..6238266)|
Detected in platelets (at protein level). Expressed by a variety of hematopoietic and epithelial cells.
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Secreted, extracellular exosome. Present at the cell surface of oocytes. Accumulates in the adhesion area between the sperm and egg following interaction between IZUMO1 and its receptor IZUMO1R/JUNO.
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