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- Table of Contents
Interleukin-18 Antibodies
AND IL18 ELISA kits, Interleukin-18 Proteins
Many biological assays use antibodies to detect Interleukin-18, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Interleukin-18 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Interleukin-18 antibodies...
Designing a Western blot for Interleukin-18? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IL18 Western Blot GuideIL18 Video by Boster Bio
All IL18 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0864
96 wells/kit, with removable strips.
Cat # EK0864
96 wells/kit, with removable strips.
Mouse IL-18 ELISA Kit PicoKine®
66 Citations
Mouse
ELISA
$499
Cat # EK0433
96 wells/kit, with removable strips.
Cat # EK0433
96 wells/kit, with removable strips.
Rat
ELISA
$399
Cat # EK0592
96 wells/kit, with removable strips.
Cat # EK0592
96 wells/kit, with removable strips.
Anti-Interleukin-18 IL18 Antibody Picoband®
7 Citations
Mouse
ELISA, IHC, WB
$370
Cat # RP1017
100 μg/vial
Cat # RP1017
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A07267-1
100 μg/vial
Cat # A07267-1
100 μg/vial
Mouse, Rat
WB, ELISA (Cap)
$370
Cat # A07261-1
100 μg/vial
Cat # A07261-1
100 μg/vial
Human IL-18R1 ELISA Kit PicoKine®
1 Citations
Human
ELISA
$499
Cat # EK1260
96 wells/kit, with removable strips.
Cat # EK1260
96 wells/kit, with removable strips.
Human, Rat
IHC, WB
$370
Cat # M07261-1
100 µl/vial
Cat # M07261-1
100 µl/vial
Human
ELISA, IP, IF, IHC, WB
$146
Cat # M00124-4
20μL, 40μL, 100μL, 200μL
Cat # M00124-4
20μL, 40μL, 100μL, 200μL
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00124-1
100 μg
Cat # M00124-1
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00124-2
100 μg
Cat # M00124-2
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00124-3
100 μg
Cat # M00124-3
100 μg
Human
Cell Culture
$77
Cat # PROTQ14116-2
5ug,20ug,100ug
Cat # PROTQ14116-2
5ug,20ug,100ug
Mouse
Cell Culture
$77
Cat # PROTP70380-4
5ug,20ug,100ug
Cat # PROTP70380-4
5ug,20ug,100ug
Human
Cell Culture
$77
Cat # PROTO95998-4
5ug,20ug,100ug
Cat # PROTO95998-4
5ug,20ug,100ug
IL18 Overview
Facts about Interleukin-18.
Interleukin-18 (IL18)
A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators (PubMed:14528293, PubMed:25500532).
Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable) (PubMed:10653850). .
Gene Information
| Human | |
|---|---|
| Gene Name: | IL18 |
| Uniprot: | Q14116 |
| Entrez: | 3606 |
Family
| Belongs to: |
|---|
| IL-1 family |
Alternative Names
Iboctadekin; IFN-gamma-inducing factor; IGIF; IGIFIL-1 gamma; IL18; IL-18; IL-18MGC12320; IL-1F4; IL1F4iboctadekin; IL-1g; Interferon gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor); Interleukin-1 gamma; interleukin-18
Molecular Weight
Mass (kDA):
22.326 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q23.1 |
| Sequence: | 11; NC_000011.10 (112143251..112164104, complement) |
Subcellular Localizations
Secreted.
Diseases
- Inflammation
- Malignant Neoplasms
- Neoplasms
- Arthritis
- Rheumatoid Arthritis
- Autoimmune Reaction
- Autoimmune Diseases
- Inflammatory Response
- Diabetes Mellitus
- Diabetes Mellitus, Insulin-dependent
- Infective Disorder
- Obesity
- Chronic Inflammation
Interacting Proteins
- IL18R1
Pathways
- Immune Response
- Pathogenesis
- Secretion
- Inflammatory Response
- Cell Proliferation
- Cytokine Production
- Sensitization
- Cell Cycle
- Cell Adhesion
- Energy Homeostasis
- Regeneration
- Coagulation
- Lymphocyte Activation
PTMs
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL18
bosterbio.com/bosterbio-gene-info-cards/IL18
References
PMID: 8666798 by Ushio S., et al. Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein.
PMID: 15326478 by Gaggero A., et al. A novel isoform of pro-interleukin-18 expressed in ovarian tumors is resistant to caspase-1 and -4 processing.
125 Publications of Boster Interleukin-18 Antibodies & ELISA Kits
- PubMed ID: PMID:28174351, Kidney Function Improvement by Soy Milk Containing Lactobacillus plantarum A7 in...
- PubMed ID: PMID:25194409, Effects of pioglitazone on blood glucose and inflammatory markers of diabetic ki...
- PubMed ID: PMID:23377818, Serum 17-OH progesterone and free testosterone levels in women patients with Fam...
- PubMed ID: 10.4103/aian.AIAN_515_18, Interleukin 18 Polymorphisms and its serum level in Patients with Multiple Scler...
- PubMed ID: 10.3892/or.2019.7270, Emodin attenuates adenosine triphosphate‑induced pancreatic ductal cell injury...
- PubMed ID: 10.3892/mmr.2018.9683, Rapamycin‑induced autophagy attenuates hormone‑imbalance‑induced chronic n...
- PubMed ID: 10.3892/mmr.2015.3620, Exogenous α-calcitonin gene-related peptide attenuates lipopolysaccharide-induc...
- PubMed ID: 10.3892/etm.2019.8327, Effect of pulegone on the NLPR3 inflammasome during inflammatory activation of T...
- PubMed ID: 10.3390/molecules25204796, Anti-Inflammatory Property of the Essential Oil from Cinnamomum camphora (Linn.)...
- PubMed ID: 10.3390/cells8080897, Parkin-Dependent Mitophagy Is Required for the Inhibition of ATF4 on NLRP3 Infla...
- PubMed ID: 10.3389/fphar.2021.722907, Protective Effect of Oxytocin on Ventilator-Induced Lung Injury Through NLRP3-Me...
- PubMed ID: 10.3389/fphar.2020.603689, H3 Relaxin Alleviates Migration, Apoptosis and Pyroptosis Through P2X7R-Mediated...
- PubMed ID: 10.3389/fphar.2019.01003, Berberine Ameliorates Spatial Learning Memory Impairment and Modulates Cholinerg...
- PubMed ID: 10.3389/fphar.2017.00334, Berberine Ameliorates Diabetes-Associated Cognitive Decline through Modulation o...
- PubMed ID: 10.3389/fonc.2019.00364, Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated...
- PubMed ID: 10.3389/fimmu.2021.739757, Sex-Related Differences in Innate and Adaptive Immune Responses to SARS-CoV-2
- PubMed ID: 10.26355/eurrev_201908_18620, Melatonin inhibits the inflammation and apoptosis in rats with diabetic retinopa...
- PubMed ID: 10.2217/bmm-2019-0124, Interleukins and miRNAs intervene in the early stages of diabetic kidney disease...
- PubMed ID: 10.2147/IJN.S106912, Exposure to nickel oxide nanoparticles induces pulmonary inflammation through NL...
- PubMed ID: 10.2147/DDDT.S164324, Theaflavin alleviates inflammatory response and brain injury induced by cerebral...
- PubMed ID: 10.21037/atm-19-1739, The activation of IL-17 signaling pathway promotes pyroptosis in pneumonia-induc...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page