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- Table of Contents
471 Citations 17 Q&As
674 Citations 10 Q&As
435 Citations 10 Q&As
11 Citations 15 Q&As
21 Citations
13 Citations 1 Q&As
12 Citations 4 Q&As
Facts about Interleukin-6.
Plays an important role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS.
Human | |
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Gene Name: | IL6 |
Uniprot: | P05231 |
Entrez: | 3569 |
Belongs to: |
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IL-6 superfamily |
B cell stimulatory factor-2; B-cell differentiation factor; BSF2; BSF-2; BSF2CTL differentiation factor; CDF; HGFHSFIFNB2Hybridoma growth factor; IFNB2; IFN-beta-2; IL6; IL-6; IL-6B-cell stimulatory factor 2; Interferon beta-2; interleukin 6 (interferon, beta 2); interleukin BSF-2; interleukin-6; MGI-2A
Mass (kDA):
23.718 kDA
Human | |
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Location: | 7p15.3 |
Sequence: | 7; NC_000007.14 (22725889..22732002) |
Secreted.
This article will explain the way in which IL-6 cytokine (also called IL-6 Recombinant proteins) can be used to diagnose cancer and to determine prognosis. IL-6 is a biomarker that can be used by researchers to determine if cancer cells are inflamed. When Boster scientists publish their research findings and share them, they earn product credits.
The IL-6 ahelical pleiotropic cell cytokine with dual anti-inflammatory as well as proinflammatory properties. It was originally recognized as a T cell derived differentiation factor, and later purified on the basis of its B cell differentiation function. However, scientists have since discovered several other functions of IL-6. This article will discuss some of the functions of IL-6, as well as examine its various names.
IL-6 is a pleiatropic a-helical cytokinolytic protein with numerous effects on various cells in the body. It enhances the production of acute phase proteins and inhibits the production of albumin. Additionally, IL-6 regulates both the acquired and innate immune responses. It enhances the differentiation of T cells with effector functions and the development of antibodies. IL-6 also promotes the proliferation and differentiation non-. It enMark6. Thme wan a contributindion facsed to differill easnames.
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PMID: 3491322 by Hirano T., et al. Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin.
PMID: 3500852 by Yasukawa K., et al. Structure and expression of human B cell stimulatory factor-2 (BSF- 2/IL-6) gene.
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