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- Table of Contents
Interleukin-18 Antibodies
AND IL18 ELISA kits, Interleukin-18 Proteins
Many biological assays use antibodies to detect Interleukin-18, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Interleukin-18 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Interleukin-18 antibodies...
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IL18 Video by Boster Bio
All IL18 Products
Product
Figures
Specificity
Applications
Price
Rat IL-18/IL-1F4/Interleukin-18 ELISA Kit PicoKine®
83 Citations 11 Q&As
Rat
ELISA
$399
Cat # EK0592
96 wells/kit, with removable strips.
Cat # EK0592
96 wells/kit, with removable strips.
Human IL-18/IL-1F4/Interleukin-18 ELISA Kit PicoKine®
68 Citations 9 Q&As
Human
ELISA
$499
Cat # EK0864
96 wells/kit, with removable strips.
Cat # EK0864
96 wells/kit, with removable strips.
Anti-Interleukin-18 IL18 Antibody Picoband®
1 Citations 15 Q&As
Human
WB
$370
Cat # PA1342
100 μg/vial
Cat # PA1342
100 μg/vial
Anti-Interleukin-18 IL18 Antibody Picoband®
1 Citations 16 Q&As
Human
IHC, WB
$370
Cat # PA2037
100 μg/vial
Cat # PA2037
100 μg/vial
Anti-IL18 Antibody Picoband®
13 Citations 18 Q&As
Mouse, Rat
ELISA, IHC, WB
$370
Cat # PB9014
100 μg/vial
Cat # PB9014
100 μg/vial
Anti-Interleukin-18 IL18 Antibody Picoband®
7 Citations 5 Q&As
Mouse
ELISA, IHC, WB
$370
Cat # RP1017
100 μg/vial
Cat # RP1017
100 μg/vial
Anti-IL18 Antibody Picoband®
6 Q&As
Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00124-1
100 μg/vial
Cat # A00124-1
100 μg/vial
Mouse IL-18 ELISA Kit PicoKine®
64 Citations
Mouse
ELISA
$499
Cat # EK0433
96 wells/kit, with removable strips.
Cat # EK0433
96 wells/kit, with removable strips.
Human
Cell Culture
$77
Cat # PROTQ14116-2
5ug,20ug,100ug
Cat # PROTQ14116-2
5ug,20ug,100ug
Mouse
Cell Culture
$77
Cat # PROTP70380-4
5ug,20ug,100ug
Cat # PROTP70380-4
5ug,20ug,100ug
Cynomolgus monkey, Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00124-1
100 μg
Cat # M00124-1
100 μg
Cynomolgus monkey, Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00124-2
100 μg
Cat # M00124-2
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00124-3
100 μg
Cat # M00124-3
100 μg
Human
ELISA, IP, IF, IHC, WB
$146
Cat # M00124-4
20μL, 40μL, 100μL, 200μL
Cat # M00124-4
20μL, 40μL, 100μL, 200μL
Mouse
Flow Cytometry, IF, ICC, WB
$370
Cat # M00124-5
100 μl/vial
Cat # M00124-5
100 μl/vial
IL18 Overview
Facts about Interleukin-18.
Interleukin-18 (IL18)
A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators (PubMed:14528293, PubMed:25500532).
Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable) (PubMed:10653850). .
Gene Information
| Human | |
|---|---|
| Gene Name: | IL18 |
| Uniprot: | Q14116 |
| Entrez: | 3606 |
Family
| Belongs to: |
|---|
| IL-1 family |
Alternative Names
Iboctadekin; IFN-gamma-inducing factor; IGIF; IGIFIL-1 gamma; IL18; IL-18; IL-18MGC12320; IL-1F4; IL1F4iboctadekin; IL-1g; Interferon gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor); Interleukin-1 gamma; interleukin-18
Molecular Weight
Mass (kDA):
22.326 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q23.1 |
| Sequence: | 11; NC_000011.10 (112143251..112164104, complement) |
Subcellular Localizations
Secreted.
Diseases
- Inflammation
- Malignant Neoplasms
- Neoplasms
- Arthritis
- Rheumatoid Arthritis
- Autoimmune Reaction
- Autoimmune Diseases
- Inflammatory Response
- Diabetes Mellitus
- Diabetes Mellitus, Insulin-dependent
- Infective Disorder
- Obesity
- Chronic Inflammation
Interacting Proteins
- IL18R1
Pathways
- Immune Response
- Pathogenesis
- Secretion
- Inflammatory Response
- Cell Proliferation
- Cytokine Production
- Sensitization
- Cell Cycle
- Cell Adhesion
- Energy Homeostasis
- Regeneration
- Coagulation
- Lymphocyte Activation
PTMs
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL18
bosterbio.com/bosterbio-gene-info-cards/IL18
References
PMID: 8666798 by Ushio S., et al. Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein.
PMID: 15326478 by Gaggero A., et al. A novel isoform of pro-interleukin-18 expressed in ovarian tumors is resistant to caspase-1 and -4 processing.
124 Publications of Boster Interleukin-18 Antibodies & ELISA Kits
- PubMed ID: PMID:28174351, Kidney Function Improvement by Soy Milk Containing Lactobacillus plantarum A7 in...
- PubMed ID: PMID:25194409, Effects of pioglitazone on blood glucose and inflammatory markers of diabetic ki...
- PubMed ID: PMID:23377818, Serum 17-OH progesterone and free testosterone levels in women patients with Fam...
- PubMed ID: 10.4103/aian.AIAN_515_18, Interleukin 18 Polymorphisms and its serum level in Patients with Multiple Scler...
- PubMed ID: 10.3892/or.2019.7270, Emodin attenuates adenosine triphosphate‑induced pancreatic ductal cell injury...
- PubMed ID: 10.3892/mmr.2018.9683, Rapamycin‑induced autophagy attenuates hormone‑imbalance‑induced chronic n...
- PubMed ID: 10.3892/mmr.2015.3620, Exogenous α-calcitonin gene-related peptide attenuates lipopolysaccharide-induc...
- PubMed ID: 10.3892/etm.2019.8327, Effect of pulegone on the NLPR3 inflammasome during inflammatory activation of T...
- PubMed ID: 10.3390/molecules25204796, Anti-Inflammatory Property of the Essential Oil from Cinnamomum camphora (Linn.)...
- PubMed ID: 10.3390/cells8080897, Parkin-Dependent Mitophagy Is Required for the Inhibition of ATF4 on NLRP3 Infla...
- PubMed ID: 10.3389/fphar.2021.722907, Protective Effect of Oxytocin on Ventilator-Induced Lung Injury Through NLRP3-Me...
- PubMed ID: 10.3389/fphar.2020.603689, H3 Relaxin Alleviates Migration, Apoptosis and Pyroptosis Through P2X7R-Mediated...
- PubMed ID: 10.3389/fphar.2019.01003, Berberine Ameliorates Spatial Learning Memory Impairment and Modulates Cholinerg...
- PubMed ID: 10.3389/fphar.2017.00334, Berberine Ameliorates Diabetes-Associated Cognitive Decline through Modulation o...
- PubMed ID: 10.3389/fonc.2019.00364, Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated...
- PubMed ID: 10.3389/fimmu.2021.739757, Sex-Related Differences in Innate and Adaptive Immune Responses to SARS-CoV-2
- PubMed ID: 10.26355/eurrev_201908_18620, Melatonin inhibits the inflammation and apoptosis in rats with diabetic retinopa...
- PubMed ID: 10.2217/bmm-2019-0124, Interleukins and miRNAs intervene in the early stages of diabetic kidney disease...
- PubMed ID: 10.2147/IJN.S106912, Exposure to nickel oxide nanoparticles induces pulmonary inflammation through NL...
- PubMed ID: 10.2147/DDDT.S164324, Theaflavin alleviates inflammatory response and brain injury induced by cerebral...
- PubMed ID: 10.21037/atm-19-1739, The activation of IL-17 signaling pathway promotes pyroptosis in pneumonia-induc...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page