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- Table of Contents
MAPK1 Antibodies
AND MAPK1 ELISA kits, MAPK1 Proteins
Many biological assays use antibodies to detect MAPK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAPK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAPK1 antibodies...
Designing a Western blot for MAPK1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MAPK1 Western Blot GuideDesigning an IHC experiment for MAPK1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MAPK1 IHC GuideMAPK1 Infographic by Boster Bio
All MAPK1 Products
Product
Figures
Specificity
Applications
Price
Anti-ERK1/2 Rabbit Monoclonal Antibody
53 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M00104-1
100 μl
Cat # M00104-1
100 μl
Anti-p38 alpha/MAPK14 Antibody Picoband®
29 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A00176-2
100 μg/vial
Cat # A00176-2
100 μg/vial
Anti-MAPK1/3 Antibody Picoband®
10 Citations
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # PA1049
100 μg/vial
Cat # PA1049
100 μg/vial
Anti-p38 MAPK MAPK14 Rabbit Monoclonal Antibody
6 Citations
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00176-1
100 μl
Cat # M00176-1
100 μl
Anti-SAPK4/MAPK13 Antibody Picoband®
1 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # PB9721
100 μg/vial
Cat # PB9721
100 μg/vial
Anti-p38 gamma/MAPK12 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A03942-1
100 μg/vial
Cat # A03942-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03738-1
100 μg/vial
Cat # A03738-1
100 μg/vial
Anti-ERK2 Monoclonal Antibody
3 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00030
100 μl
Cat # M00030
100 μl
Human
IHC, WB
$370
Cat # M00176T180
100 µl/vial
Cat # M00176T180
100 µl/vial
Anti-p38 MAPK14 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M00176
100 μl
Cat # M00176
100 μl
Anti-JNK3 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M04297
100 μl
Cat # M04297
100 μl
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00030Y222
100ul
Cat # A00030Y222
100ul
Guinea pig, Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$380
Cat # A00176T180Y182
100ul
Cat # A00176T180Y182
100ul
Anti-JNK/MAPK10 Antibody
1 Citations
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A04297-2
100 μl/vial
Cat # A04297-2
100 μl/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00030-2
20μL, 40μL, 100μL, 200μL
Cat # M00030-2
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA, IP, IF, WB
$146
Cat # M00030-3
20μL, 40μL, 100μL, 200μL
Cat # M00030-3
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA, IP, IF, WB
$146
Cat # M02608-5
20μL, 40μL, 100μL, 200μL
Cat # M02608-5
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA, IP, IF, WB
$146
Cat # M00176-4
20μL, 40μL, 100μL, 200μL
Cat # M00176-4
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA
$480
Cat # EKC1702
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1702
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2485
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2485
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2484
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2484
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2198
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2198
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1422
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1422
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
ELISA
$480
Cat # EKC1201
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1201
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2257
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2257
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2199
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2199
1 kit, containing two 96-well plates and all necessary reagents
Anti-Phospho-p38 MAPK/MAPK14 (Y182) Antibody
3 Citations
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # P00176-2
100 μl/vial
Cat # P00176-2
100 μl/vial
MAPK1 Overview
Facts about Mitogen-activated protein kinase 1.
Mitogen-activated protein kinase 1 (MAPK1)
Serine/threonine kinase which acts as an important part of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 will be the 2 MAPKs which play an significant role in the MAPK/ERK cascade.
They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Based on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Gene Information
| Human | |
|---|---|
| Gene Name: | MAPK1 |
| Uniprot: | P28482 |
| Entrez: | 5594 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
EC 2.7.11; EC 2.7.11.24; ERK; ERK2; ERK-2; ERK2MAP kinase isoform p42; ERT1; Extracellular signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAPK 1; MAPK1; MAPK2; mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; p38; p40; p41; p41mapk; p42mapk; p42-MAPK; PRKM1; PRKM1MAPK 2; PRKM2; protein tyrosine kinase ERK2
Molecular Weight
Mass (kDA):
41.39 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q11.22 |
| Sequence: | 22; NC_000022.11 (21759657..21867680, complement) |
Subcellular Localizations
Cytoplasm, cytoskeleton, spindle. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Membrane, caveola. Associated with the spindle during prometaphase and metaphase (By similarity). PEA15-binding and phosphorylated DAPK1 promote its cytoplasmic retention. Phosphorylation at Ser- 246 and Ser-248 as well as autophosphorylation at Thr-190 promote nuclear localization.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Inflammation
- Cell Invasion
- Tissue Adhesions
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Neoplasm Metastasis
- Tumor Angiogenesis
- Cell Transformation, Neoplastic
- Neoplasm Invasiveness
Interacting Proteins
- ARRB2
- BLVRA
- COPS6
- DUSP1
- Dusp2
- DUSP4
- DUSP5
- ETS1
- MAP2K1
- MAPK3
Pathways
- Cell Proliferation
- Cell Cycle
- Cell Death
- Cell Growth
- Secretion
- Pathogenesis
- Angiogenesis
- Cell Migration
- Localization
- Cell Adhesion
- Cell Differentiation
- Translation
- Transport
PTMs
- Phosphorylation
- Cleavage
- Dephosphorylation
- Ubiquitination
- Methylation
- Reduction
- Acetylation
Research Areas
- Angiogenesis
- Apoptosis
- Breast Cancer
- Cancer
- Diabetes Research
- Hypoxia
- Phospho-Specific
- Protein Kinase
- Signal Transduction
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAPK1
bosterbio.com/bosterbio-gene-info-cards/MAPK1
References
PMID: 1540184 by Owaki H., et al. Extracellular signal-regulated kinases in T cells: characterization of human ERK1 and ERK2 cDNAs.
PMID: 1319925 by Gonzalez F.A., et al. Heterogeneous expression of four MAP kinase isoforms in human tissues.
29 Publications of Boster MAPK1 Antibodies & ELISA Kits
- PubMed ID: 10.3892/or.2017.5861, Pseudolaric acid B inhibits neuroglioma cell proliferation through DNA damage re...
- PubMed ID: 10.3892/mmr.2019.10785, Placental growth factor gene silencing mitigates the epithelial‑to‑mesenchym...
- PubMed ID: 10.26355/eurrev_201812_16641, CXCL13 inhibition induce the apoptosis of MDA-MB-231 breast cancer cells through...
- PubMed ID: 10.18632/aging.102743, The protein tyrosine kinase inhibitor, Genistein, delays intervertebral disc deg...
- PubMed ID: 10.1016/j.jep.2017.03.012, The vascular protective effects of Anoectochilus roxburghii polysaccharose under...
- PubMed ID: 10.1016/j.ijbiomac.2017.05.191, β-d-glucan from Antrodia Camphorata ameliorates LPS-induced inflammation and RO...
- PubMed ID: 10.1007/s12031-017-0994-x, Let-7d microRNA Attenuates 6-OHDA-Induced Injury by Targeting Caspase-3 in MN9D ...
- PubMed ID: 31611791, Wei X,Zhu Q,Liu N,Xu L,Wei S,Fan Z,Sun C,Zhao Y,Qiao M,Wu J,Hu D,Wang Y,Sun P.Ne...
- PubMed ID: 33856409, Wu T,Liu Q,Li Y,Li H,Chen L,Yang X,Tang Q,Pu S,Kuang J,Li R,Huang Y,Zhang J,Zhan...
- PubMed ID: -, Huanyue Cui,Xueying Liu,Jin Zhang,Ke Zhang,Dahong Yao,Shi Dong,Shushu Feng,Lu Ya...
- PubMed ID: -, Feng,S.,Wang,S.,Sun,S.,Su,H.,& Zhang,L.(2021).Effects of combination treatment w...
- PubMed ID: 32794226, Ma G,Kimatu BM,Yang W,Pei F,Zhao L,Du H,Su A,Hu Q,Xiao H.Preparation of newly id...
- PubMed ID: 33242618, Lin S,Li Q,Jiang S,Xu Z,Jiang Y,Liu L,Jiang J,Tong Y,Wang P.Crocetin ameliorates...
- PubMed ID: 31611791, Neuroprotective Effects and Mechanisms of Zhenlong Xingnao Capsule in In Vivo an...
- PubMed ID: 22272075, Inhibition of extracellular signal-regulated kinases ameliorates hypertension-in...
- PubMed ID: 21985377, Synthesis and biological evaluation of novel N, N%u2032-disubstituted urea and t...
- PubMed ID: 26517513, Disulfiram inhibits TGF-?-induced epithelial-mesenchymal transition and stem-lik...
- PubMed ID: 28193911, eIF3i activity is critical for endothelial cells in tumor induced angiogenesis t...
- PubMed ID: 25864648, Fructus phyllanthi tannin fraction induces apoptosis and inhibits migration and ...
- PubMed ID: 25206865, Vasopressin decreases neuronal apoptosis during cardiopulmonary resuscitation
- PubMed ID: 24083559, Astragalus injection protects cerebral ischemic injury by inhibiting neuronal ap...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page