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UDP-glucose 4-epimerase Antibodies
AND GALE ELISA kits, UDP-glucose 4-epimerase Proteins
Many biological assays use antibodies to detect UDP-glucose 4-epimerase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UDP-glucose 4-epimerase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UDP-glucose 4-epimerase antibodies...
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GALE Infographic by Boster Bio
All GALE Products
Product
Figures
Specificity
Applications
Price
Dog, Human, Monkey, Mouse, Rat
IHC, WB
$523
Cat # M00551
100 µl
Cat # M00551
100 µl
GALE Overview
Facts about UDP-glucose 4-epimerase.
UDP-glucose 4-epimerase (GALE)
Catalyzes two different but analogous responses: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The response with UDP-Gal plays a crucial role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6- phosphate.
It contributes to the catabolism of dietary galactose and empowers the endogenous biosynthesis of both UDP-Gal and UDP- GalNAc when exogenous resources are limited. The two UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
Gene Information
| Human | |
|---|---|
| Gene Name: | GALE |
| Uniprot: | Q14376 |
| Entrez: | 2582 |
Family
| Belongs to: |
|---|
| NAD(P)-dependent epimerase/dehydratase family |
Alternative Names
EC 5.1.3; EC 5.1.3.2; FLJ95174; FLJ97302; Galactowaldenase; short chain dehydrogenase/reductase family 1E, member 1; UDP galactose-4'-epimerase; UDP-; UDP-galactose 4-epimerase; UDP-galactose-4-epimerase; UDP-glucose 4-epimerase
Molecular Weight
Mass (kDA):
38.282 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.11 |
| Sequence: | 1; NC_000001.11 (23795599..23800754, complement) |
Diseases
- Udpglucose 4-epimerase Deficiency Disease
- Salmonella Infections
- Classical Galactosemia
- Deficiency Of Galactokinase
- Galactosemias
- Influenza
- Tissue Adhesions
- Deficiency Of Epimerase
- Typhoid Fever
- Malignant Neoplasms
- Diabetes Mellitus, Insulin-dependent
- Inborn Errors Of Metabolism
- Cell Invasion
Pathways
- Virulence
- Transport
- Translation
- Glycosylation
- Biofilm Formation
- Localization
- Cell Proliferation
- Pathogenesis
- Excretion
- Immune Response
- Nodulation
- Locomotion
- Colony Morphology
PTMs
- Glycosylation
- Methylation
- Deglycosylation
- Phosphorylation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GALE
bosterbio.com/bosterbio-gene-info-cards/GALE
References
PMID: 8593531 by Daude N., et al. Molecular cloning, characterization, and mapping of a full-length cDNA encoding human UDP-galactose 4'-epimerase.
PMID: 9538513 by Maceratesi P., et al. Human UDP-galactose 4'epimerase (GALE) gene and identification of five missense mutations in patients with epimerase deficiency galactosemia.