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- Table of Contents
Interleukin-1 beta Antibodies
AND IL1B ELISA kits, Interleukin-1 beta Proteins
Many biological assays use antibodies to detect Interleukin-1 beta, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Interleukin-1 beta in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Interleukin-1 beta antibodies...
Designing a Western blot for Interleukin-1 beta? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IL1B Western Blot GuideIL1B Infographic by Boster Bio
All IL1B Products
Product
Figures
Specificity
Applications
Price
Mouse
ELISA
$399
Cat # EK0394
96 wells/kit, with removable strips.
Cat # EK0394
96 wells/kit, with removable strips.
Human
ELISA
$399
Cat # EK0392
96 wells/kit, with removable strips.
Cat # EK0392
96 wells/kit, with removable strips.
Rat
ELISA
$399
Cat # EK0393
96 wells/kit, with removable strips.
Cat # EK0393
96 wells/kit, with removable strips.
Anti-IL1 beta/IL1B Antibody Picoband®
21 Citations
Mouse, Rat
ELISA, IHC, WB
$370
Cat # PB9025
100 μg/vial
Cat # PB9025
100 μg/vial
Human
ELISA
$500
Cat # EZ0392
For 5 plates, 96 wells each
Cat # EZ0392
For 5 plates, 96 wells each
Mouse
ELISA
$500
Cat # EZ0394
For 5 plates, 96 wells each, reagents only, plates are not included
Cat # EZ0394
For 5 plates, 96 wells each, reagents only, plates are not included
Mouse
ELISA
$499
Cat # FEK0394
96 wells/kit, with removable strips.
Cat # FEK0394
96 wells/kit, with removable strips.
Human IL-1β PicoKine® Quick ELISA Kit
2 Citations
Human
ELISA
$499
Cat # FEK0392
96 wells/kit, with removable strips.
Cat # FEK0392
96 wells/kit, with removable strips.
Rat
ELISA
$499
Cat # FEK0393
96 wells/kit, with removable strips.
Cat # FEK0393
96 wells/kit, with removable strips.
Human, Mouse, Rat
IP, WB
$370
Cat # M00048-2
100 μl/vial
Cat # M00048-2
100 μl/vial
Mouse, Rat
Flow Cytometry, IP, WB
$370
Cat # M00101-3
100 μl/vial
Cat # M00101-3
100 μl/vial
Mouse
ELISA
$519
Cat # HSEK0394
96 wells/kit, with removable strips.
Cat # HSEK0394
96 wells/kit, with removable strips.
Monkey
ELISA
$499
Cat # EK2377
96 wells/kit, with removable strips.
Cat # EK2377
96 wells/kit, with removable strips.
Feline
ELISA
$499
Cat # EK2371
96 wells/kit, with removable strips.
Cat # EK2371
96 wells/kit, with removable strips.
Equine
ELISA
$499
Cat # EK2364
96 wells/kit, with removable strips.
Cat # EK2364
96 wells/kit, with removable strips.
Porcine
ELISA
$499
Cat # EK2348
96 wells/kit, with removable strips.
Cat # EK2348
96 wells/kit, with removable strips.
Canine
ELISA
$499
Cat # EK2338
96 wells/kit, with removable strips.
Cat # EK2338
96 wells/kit, with removable strips.
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01144-3
100 μg
Cat # M01144-3
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00101-7
100 μg
Cat # M00101-7
100 μg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00101-6
100 μg
Cat # M00101-6
100 μg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00101-5
100 μg
Cat # M00101-5
100 μg
Mouse IL-1 beta /IL-1F2 Recombinant Protein
2 Citations
SDS-PAGE, Bioactivity
$281
Cat # PROTP10749
Starting from 10ug
Cat # PROTP10749
Starting from 10ug
Swine
Cell Culture
$154
Cat # PROTP26889-1
5ug,20ug
Cat # PROTP26889-1
5ug,20ug
Mouse
Cell Culture
$77
Cat # PROTP10749-5
5ug,20ug,100ug
Cat # PROTP10749-5
5ug,20ug,100ug
Human
Cell Culture
$77
Cat # PROTP01584-5
5ug,20ug,100ug
Cat # PROTP01584-5
5ug,20ug,100ug
SDS-PAGE, Bioactivity
$300
Cat # PROTQ2VCE2
Starting from 10ug
Cat # PROTQ2VCE2
Starting from 10ug
IL1B Overview
Facts about Interleukin-1 beta.
Interleukin-1 beta (IL1B)
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.
Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed:10653850).
Gene Information
| Human | |
|---|---|
| Gene Name: | IL1B |
| Uniprot: | P01584 |
| Entrez: | 3553 |
Family
| Belongs to: |
|---|
| IL-1 family |
Alternative Names
catabolin; IL1 beta; IL-1 beta; IL-1; IL1B; IL-1b; IL1-BETA; IL-1F2; IL1F2IL-1 beta; interleukin 1, beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta
Molecular Weight
Mass (kDA):
30.748 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q14.1 |
| Sequence: | 2; NC_000002.12 (112829751..112836843, complement) |
Tissue Specificity
Expressed in activated monocytes/macrophages (at protein level).
Subcellular Localizations
Cytoplasm, cytosol. Lysosome. Secreted, extracellular exosome. Secreted. The precursor is cytosolic. In response to inflammasome-activating signals, such as ATP for NLRP3 inflammasome or bacterial flagellin for NLRC4 inflammasome, cleaved and secreted. IL1B lacks any known signal sequence and the pathway(s) of its secretion is(are) not yet fully understood (PubMed:24201029). On the basis of experimental results, several unconventional secretion mechanisms have been proposed. 1. Secretion via secretory lysosomes: a fraction of CASP1 and IL1B precursor may be incorporated, by a yet undefined mec
Diseases
- Inflammation
- Malignant Neoplasms
- Inflammatory Response
- Variable Number Tandem Repeat
- Dysequilibrium Syndrome
- Cholangiocarcinoma
- Malignant Neoplasm Of Stomach
- Arthritis
- Neoplasms
- Diabetes Mellitus
- Carcinogenesis
- Stomach Neoplasms
- Degenerative Polyarthritis
Pathways
- Pathogenesis
- Inflammatory Response
- Immune Response
- Secretion
- Cytokine Production
- Innate Immune Response
- Localization
- Cell Proliferation
- Methylation
- Parturition
- Angiogenesis
- Fertilization
- Cell Cycle
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL1B
bosterbio.com/bosterbio-gene-info-cards/IL1B
References
PMID: 6083565 by Auron P.E., et al. Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.
PMID: 2989698 by March C.J., et al. Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs.
1163 Publications of Boster Interleukin-1 beta Antibodies & ELISA Kits
- PubMed ID: PMID:33312354, The mobilization of splenic reservoir myeloid-derived suppressor cells in sepsis...
- PubMed ID: PMID:29423011, Luteolin alleviates NLRP3 inflammasome activation and directs macrophage polariz...
- PubMed ID: PMID:29312516, Salvianolic acid A attenuates early brain injury after subarachnoid hemorrhage i...
- PubMed ID: PMID:28485792, Increased expression of CXCR5 and CXCL13 in mice with experimental autoimmune my...
- PubMed ID: PMID:26191183, Unfractionated heparin attenuates intestinal injury in mouse model of sepsis by ...
- PubMed ID: PMID:25419373, Toll-like receptor 4 implicated in acute lung injury induced by paraquat poisoni...
- PubMed ID: PMID:23377818, Serum 17-OH progesterone and free testosterone levels in women patients with Fam...
- PubMed ID: 10.7150/thno.45455, Indoxyl sulfate induces intestinal barrier injury through IRF1-DRP1 axis-mediate...
- PubMed ID: 10.5551/jat.29421, Interleukin-1 Receptor-Associated Kinase 1/4 as a Novel Target for Inhibiting Ne...
- PubMed ID: 10.4168/aair.2021.13.1.88, The Role of Macrophage Migration Inhibitory Factor (MIF) in Asthmatic Airway Rem...
- PubMed ID: 10.4103/1673-5374.264465, Characterization of astrocytes and microglial cells in the hippocampal CA1 regio...
- PubMed ID: 10.4103/1673-5374.247465, Acacetin protects against cerebral ischemia-reperfusion injury via the NLRP3 sig...
- PubMed ID: 10.4049/jimmunol.1900083, USP19 Inhibits TNF-α– and IL-1β–Triggered NF-κB Activation by Deubiquitin...
- PubMed ID: 10.4049/jimmunol.179.2.1236, The Anti-inflammatory Effects of Heat Shock Protein 72 Involve Inhibition of Hig...
- PubMed ID: 10.3892/or.2019.7270, Emodin attenuates adenosine triphosphate‑induced pancreatic ductal cell injury...
- PubMed ID: 10.3892/ol.2018.8510, Signaling via the CXCR5/ERK pathway is mediated by CXCL13 in mice with breast ca...
- PubMed ID: 10.3892/mmr.2020.11675, Ginsenoside Rg1 improves pathological damages by activating the p21‑p53�...
- PubMed ID: 10.3892/mmr.2019.10746, Exopolysaccharide from Paecilomyces lilacinus modulates macrophage activities th...
- PubMed ID: 10.3892/mmr.2019.10113, Protective effects of propofol on experimental neonatal acute lung injury
- PubMed ID: 10.3892/mmr.2018.9683, Rapamycin‑induced autophagy attenuates hormone‑imbalance‑induced chronic n...
- PubMed ID: 10.3892/mmr.2018.9262, ‘Psoriasis 1’ reduces psoriasis‑like skin inflammation by inhibiting the V...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page