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- Table of Contents
Interstitial collagenase Antibodies
AND MMP1 ELISA kits, Interstitial collagenase Proteins
Many biological assays use antibodies to detect Interstitial collagenase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Interstitial collagenase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Interstitial collagenase antibodies...
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MMP1 Infographic by Boster Bio
All MMP1 Products
Product
Figures
Specificity
Applications
Price
Human MMP-1 ELISA Kit PicoKine®
26 Citations 10 Q&As
Human
ELISA
$499
Cat # EK0458
96 wells/kit, with removable strips.
Cat # EK0458
96 wells/kit, with removable strips.
Anti-MMP1 Rabbit Monoclonal Antibody
1 Citations 16 Q&As
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00733
100 μl
Cat # M00733
100 μl
Anti-MMP1 Antibody Picoband®
17 Citations 5 Q&As
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00733-1
100 μg/vial
Cat # A00733-1
100 μg/vial
Human MMP-1 PicoKine® Quick ELISA Kit
2 Citations
Human
ELISA
$499
Cat # FEK0458
96 wells/kit, with removable strips.
Cat # FEK0458
96 wells/kit, with removable strips.
MMP1 Overview
Facts about Interstitial collagenase.
Interstitial collagenase (MMP1)
Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X (PubMed:2557822, PubMed:2153297, PubMed:1645757).
In case of HIV infection, interacts and cleaves the secreted viral Tat protein, resulting in a decrease in neuronal Tat's mediated neurotoxicity (PubMed:16807369). .
Gene Information
| Human | |
|---|---|
| Gene Name: | MMP1 |
| Uniprot: | P03956 |
| Entrez: | 4312 |
Family
| Belongs to: |
|---|
| peptidase M10A family |
Alternative Names
CLGmatrix metalloprotease 1; CLGN; EC 3.4.24; EC 3.4.24.7; Fibroblast collagenase; interstitial collagenase; matrix metallopeptidase 1 (interstitial collagenase); matrix metalloproteinase 1 (interstitial collagenase); Matrix metalloproteinase-1; MMP1; MMP-1
Molecular Weight
Mass (kDA):
54.007 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q22.2 |
| Sequence: | 11; NC_000011.10 (102789919..102798160, complement) |
Subcellular Localizations
Secreted, extracellular space, extracellular matrix.
Diseases
- Malignant Neoplasms
- Neoplasms
- Cell Invasion
- Neoplasm Metastasis
- Carcinoma
- Inflammation
- Neoplasm Invasiveness
- Fibrosis
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Degenerative Polyarthritis
- Malignant Squamous Cell Neoplasm
- Tissue Adhesions
Pathways
- Pathogenesis
- Secretion
- Wound Healing
- Angiogenesis
- Cell Proliferation
- Tissue Remodeling
- Cell Migration
- Localization
- Cell Cycle
- Aging
- Cell Adhesion
- Cell Death
- Regeneration
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Sumoylation
- Sulphation
- Nitrosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MMP1
bosterbio.com/bosterbio-gene-info-cards/MMP1
References
PMID: 2167156 by Templeton N.S., et al. Cloning and characterization of human tumor cell interstitial collagenase.
PMID: 3030290 by Whitham S.E., et al. Comparison of human stromelysin and collagenase by cloning and sequence analysis.
55 Publications of Boster Interstitial collagenase Antibodies & ELISA Kits
- PubMed ID: PMID:25337218, Effects of hydroxysafflor yellow A on proliferation and collagen synthesis of ra...
- PubMed ID: 10.3980/j.issn.2222-3959.2011.04.05, Detection and comparison of matrix metalloproteinase in primary and recurrent pt...
- PubMed ID: 10.3892/mmr.2017.6532, MALAT1 participates in ultraviolet B-induced photo-aging via regulation of the E...
- PubMed ID: 10.3892/mmr.2016.6026, Ganoderma lucidum polysaccharides protect fibroblasts against UVB-induced photoa...
- PubMed ID: 10.3892/etm.2015.2194, Decreased expression of matrix metalloproteinase-1 in the maternal umbilical ser...
- PubMed ID: 10.3390/ijms22168980, A Combination of Celecoxib and Glucosamine Sulfate Has Anti-Inflammatory and Cho...
- PubMed ID: 10.2147/CMAR.S233776, MMP-2, MMP-9, TIMP-1, and TIMP-2 in the Peripheral Blood of Patients with Differ...
- PubMed ID: 10.1111/php.13156, Protective Effects of Ginseng Proteins on Photoaging of Mouse Fibroblasts Induce...
- PubMed ID: 10.1080/07315724.2015.1068139, Effects of l-Carnitine Supplementation on Serum Inflammatory Factors and Matrix...
- PubMed ID: 10.1038/srep21190, Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic ...
- PubMed ID: 10.1038/s41419-021-03802-9, Metalloproteinase 1 downregulation in neurofibromatosis 1: Therapeutic potential...
- PubMed ID: 10.1016/j.phymed.2017.10.016, Anti-inflammatory and anti-arthritic effects of the ethanolic extract of Aralia ...
- PubMed ID: 10.1016/j.pep.2018.04.001, Efficient protease based purification of recombinant matrix metalloprotease-1 in...
- PubMed ID: 10.1016/j.jbc.2021.101166, Type 2 diabetic mice enter a state of spontaneous hibernation-like suspended ani...
- PubMed ID: 10.1016/j.intimp.2018.10.004, Methylsulfonylmethane and mobilee prevent negative effect of IL-1β in human cho...
- PubMed ID: 10.1016/j.freeradbiomed.2021.01.032, Anti-ageing effects of ubiquinone and ubiquinol in a senescence model of human d...
- PubMed ID: 10.1016/j.abb.2010.05.009, HER2-mediated upregulation of MMP-1 is involved in gastric cancer cell invasion
- PubMed ID: 10.1007/s10571-009-9409-z, IL-17 Stimulates Migration of Carotid Artery Vascular Smooth Muscle Cells in an ...
- PubMed ID: 10.1007/s10067-019-04723-x, Effects of coenzyme Q10 supplementation on matrix metalloproteinases and DAS-28 ...
- PubMed ID: 10.1002/jcb.28098, Carvacrol suppresses inflammatory responses in rheumatoid arthritis fibroblast...
- PubMed ID: 34011935, Tsuji G,Takai-Yumine A,Kato T,Furue M.Metalloproteinase 1 downregulation in neur...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page