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- Table of Contents
CD2 Antibodies
AND CD2 ELISA kits, CD2 Proteins
Many biological assays use antibodies to detect CD2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD2 antibodies...
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CD2 Infographic by Boster Bio
All CD2 Products
Product
Figures
Specificity
Applications
Price
Anti-CD2 Monoclonal Antibody
16 Q&As
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00570
100 μl
Cat # M00570
100 μl
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00570
100ul
Cat # A00570
100ul
Human, Mouse, Rat
IF, IHC
$380
Cat # M00570-1
100ul
Cat # M00570-1
100ul
Dog, Human, Mouse, Rat
Flow Cytometry, IHC, WB
$523
Cat # M00570-2
100 µl
Cat # M00570-2
100 µl
Human
ELISA, Flow Cytometry, IP, IHC, WB
$370
Cat # A00570-3
100 μg/vial
Cat # A00570-3
100 μg/vial
Cynomolgus monkey, Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00570-3
100 μg
Cat # M00570-3
100 μg
CD2 Overview
Facts about T-cell surface antigen CD2.
T-cell surface antigen CD2 (CD2)
CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T- cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CD2 |
| Uniprot: | P06729 |
| Entrez: | 914 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD2 antigen (p50), sheep red blood cell receptor; CD2 antigen; CD2 molecule; CD2; Erythrocyte receptor; FLJ46032; LFA-2; LFA-3 receptor; lymphocyte-function antigen-2; Rosette receptor; SRBC; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5
Molecular Weight
Mass (kDA):
39.448 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p13.1 |
| Sequence: | 1; NC_000001.11 (116754430..116769229) |
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Leukemia
- Neoplasms
- Lymphoma
- Malignant Neoplasms
- T-cell Lymphoma
- Leukemia, Myelocytic, Acute
- Immunologic Deficiency Syndromes
- Malignant Paraganglionic Neoplasm
- Acute Lymphocytic Leukemia
- Inflammation
- Myeloid Leukemia
- Autoimmune Reaction
Interacting Proteins
- CD2AP
- CD2BP2
- SH3KBP1
Pathways
- Cell Activation
- T Cell Activation
- Cell Adhesion
- Secretion
- Cell Proliferation
- Immune Response
- T Cell Proliferation
- Pathogenesis
- Cytokine Production
- Lymphocyte Activation
- Cell Differentiation
- Cell Development
- Cell Death
PTMs
- Phosphorylation
- Glycosylation
- Dephosphorylation
- Cleavage
- Methylation
- Biotinylation
- Reduction
- Deglycosylation
- Ribosylation
- Demethylation
Research Areas
- Adaptive Immunity
- Apoptosis
- Immunology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD2
bosterbio.com/bosterbio-gene-info-cards/CD2
References
PMID: 2894031 by Diamond D.J., et al. Exon-intron organization and sequence comparison of human and murine T11 (CD2) genes.
PMID: 2437578 by Seed B., et al. Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.