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Hr Antibodies

AND Hr ELISA kits, Hr Proteins

Many biological assays use antibodies to detect Hr, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hr in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hr antibodies...

We validate the specificity of these antibodies to Hr by testing them on tissues known to express Hr positively and negatively. Browse below to find the Hr antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Hr Infographic by Boster Bio

Hr protein infographic

All Hr Products

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Product

Figures

Specificity

Applications

Price

Anti-Hairless HR Antibody

Western blot analysis of extracts of various cell lines, using HR antibody at 1:3000 dilution

Western blot analysis of extracts of various cell lines, using HR antibody at 1:3000 dilution

Human, Mouse, Rat

WB

$405
Cat # A04817-1
100ul

Anti-Hairless (E77) HR Antibody

Western blot (WB) analysis of HR pAb at 1:500 dilution
Lane1:The Small intestine tissue lysate of Rat(40ug)
Lane2:A375 whole cell lysate(40ug)

Western blot (WB) analysis of HR pAb at 1:500 dilution
Lane1:The Small intestine tissue lysate of Rat(40ug)
Lane2:A375 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Hairless (E77) pAb in paraffin-embedded human breast carcinoma tissue at 1:50

Human, Mouse, Rat

IHC

$405
Cat # A04817-2
100ul

Hairless (HR) (NM_018411) Human Recombinant Protein

Coomassie blue staining of purified HR protein

Coomassie blue staining of purified HR protein

$1062
Cat # PROTO43593
20 µg

Anti-Hairless (HR) Mouse Monoclonal Antibody [Clone ID: OTI1D9]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HR (Right lane) cDNA for 48 hrs and lysed

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HR (Right lane) cDNA for 48 hrs and lysed

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-HR mouse monoclonal antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-HR mouse monoclonal antibody

Human

IHC, WB

$523
Cat # M04817
100 µl

Hairless (HR) (NM_005144) Human Over-expression Lysate

Hairless (HR) Human Over-expression Lysates NM_005144

Hairless (HR) Human Over-expression Lysates NM_005144

Hairless (HR) Human Over-expression Lysates NM_018411

Human

$628
Cat # LS055806
20 µg, 100 µg

Hr Overview

Facts about Lysine-specific demethylase hairless.

Lysine-specific demethylase hairless (Hr)

Histone demethylase that specifically demethylates both mono- and dimethylated'Lys-9' of histone H3. May act as a transcription regulator controlling hair biology (through targeting of collagens), neural activity, and cell cycle (By similarity).

. .

Gene Information

Mouse
Gene Name:	Hr
Uniprot:	Q61645
Entrez:	15460

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

ALUNC; AU; AUHSA277165; FLJ98880; hairless (mouse) homolog; hairless homolog (mouse); Hairless; HR; MUHH; MUHH1; protein hairless

Molecular Weight

Mass (kDA):
127.193 kDA

Molecular Weight

Genomic Context


Mouse

Location:	14\|14 D2
Sequence:	14;

Tissue Specificity

Expressed predominantly in brain, hair follicles and interfollicular epidermis. No expression in dermis.

Diseases

Atrichia
Acute Promyelocytic Leukemia
Alopecia Universalis
Hypotrichosis
Neoplasms
Hair Diseases
Dermatologic Disorders
Skin Diseases, Papulosquamous
Marie Unna Hereditary Hypotrichosis
Skin Diseases, Genetic
Carcinoma
Rickets

Obesity
Insulin Resistance
Skin Neoplasms
Headache
Transfusion Reaction
Neoplasms, Radiation-induced
Erythema

Disease

Pathways

Hair Cycle
Catagen
Localization
Pathogenesis
Regeneration
Transport
Sensitization
Hair Follicle Morphogenesis
Cell Proliferation
Aging
Keratinocyte Differentiation
Cell Adhesion
Cell Differentiation

Anagen
Chromatin Remodeling
Translation
Cell Cycle
Wound Healing
Immune Response
Pigmentation

Pathways

PTMs

Oxidation
Carboxylation
Demethylation

Phosphorylation
Reduction
Cleavage

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Hr

References

PMID: 8052649 by Cachon-Gonzalez M.B., et al. Structure and expression of the hairless gene of mice.