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- Table of Contents
Facts about Keratocan.
| Human | |
|---|---|
| Gene Name: | KERA |
| Uniprot: | O60938 |
| Entrez: | 11081 |

| Belongs to: |
|---|
| small leucine-rich proteoglycan (SLRP) family |

CNA2; KERA; Keratocan; KTN; SLRR2B; SLRR2BKeratan sulfate proteoglycan keratocan
Mass (kDA):
40.509 kDA

| Human | |
|---|---|
| Location: | 12q21.33 |
| Sequence: | 12; NC_000012.12 (91050491..91058024, complement) |
Cornea (at protein level) (PubMed:10802664, PubMed:11683372). Increased expression in the stroma of keratoconus corneas (PubMed:11683372). Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen (PubMed:10802664).
Secreted, extracellular space, extracellular matrix.




PMID: 10565548 by Tasheva E.S., et al. Structure and sequence of the gene encoding human keratocan.
PMID: 10802664 by Pellegata N.S., et al. Mutations in KERA, encoding keratocan, cause cornea plana.