Many biological assays use antibodies to detect Syncytin-A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Syncytin-A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Syncytin-A antibodies...
We validate the specificity of these antibodies to Syncytin-A by testing them on tissues known to express Syna positively and negatively. Browse below to find the Syna antibody that suites your experiment. We have 78 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
This endogenous retroviral envelope protein has retained its original fusogenic properties (PubMed:15644441, PubMed:17762178, PubMed:18077339, PubMed:19564597, PubMed:27589388). Together with Synb, participates in trophoblast fusion and the formation of a syncytium through placenta morphogenesis (PubMed:19564597).
Syna is vital for placental development and is especially required for formation of syncytiotrophoblast layer I (SynT-I) (PubMed:19564597). Promotes muscle myoblast fusion (PubMed:27589388).
Gene Information
Mouse
Gene Name:
Syna
Uniprot:
Q5G5D5
Entrez:
214292
Family
Belongs to:
gamma type-C retroviral envelope protein family
Alternative Names
Syncytin-A
Molecular Weight
Mass (kDA): 68.657 kDA
Genomic Context
Mouse
Location:
5|5 G2
Sequence:
5;
Tissue Specificity
Highly expressed in placenta where it localizes to syncytiotrophoblasts of the labyrinthine zona (PubMed:15644441). Specifically localizes to syncytiotrophoblast layer I (SynT-I) (PubMed:18448564). Also detected at very low levels in hippocampus, brain, testis and ovary (PubMed:15644441).
PTMs
Cleavage on pair of basic residues
Disulfide bond
Glycoprotein
For details, visit: bosterbio.com/bosterbio-gene-info-cards/Syna
References
PMID: 15644441 by Dupressoir A., et al. Syncytin-A and syncytin-B, two fusogenic placenta-specific murine envelope genes of retroviral origin conserved in Muridae.
PMID: 17762178 by Gong R., et al. Syncytin-A mediates the formation of syncytiotrophoblast involved in mouse placental development.
28 Publications of Boster Syncytin-A Antibodies & ELISA Kits
PubMed ID: 10.1167/iovs.09-4504, Generation of Retinal Ganglion–like Cells from Reprogrammed Mouse Fibroblasts