Pol Antibodies

AND Pol ELISA kits, Pol Proteins

Many biological assays use antibodies to detect Pol, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pol in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pol antibodies...

We validate the specificity of these antibodies to Pol by testing them on tissues known to express Pol positively and negatively. Browse below to find the Pol antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Pol Infographic by Boster Bio

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Pol Overview

Facts about Retrovirus-related Pol polyprotein.

Pol 3D structure. Source: alphafold

Retrovirus-related Pol polyprotein (Pol)

Has a reverse transcriptase activity needed for target-primed reverse transcription of the LINE-1 element mRNA, a vital step in LINE-1 retrotransposition. Has also an endonuclease activity which allows the introduction of nicks in the chromosomal target DNA.

Cleaves DNA in AT-rich regions between a 5' stretch of purines and a 3' stretch of pyrimidines, corresponding to sites of LINE-1 integration in the genome. .

Gene Information

Mouse
Gene Name:	Pol
Uniprot:	P10400
Entrez:

Family

Belongs to:

No superfamily

Alternative Names

Retrovirus-related Pol polyprotein

Molecular Weight

Mass (kDA):
13.302 kDA

Genomic Context


Mouse

Location:
Sequence:	;

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Pol

References

PMID: 2415714 by Levy D.E., et al. Normal expression of polymorphic endogenous retroviral RNA containing segments identical to mink cell focus-forming virus.