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- Table of Contents
Renin Antibodies
AND REN ELISA kits, Renin Proteins
Many biological assays use antibodies to detect Renin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Renin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Renin antibodies...
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REN Infographic by Boster Bio
All REN Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1249
96 wells/kit, with removable strips.
Cat # EK1249
96 wells/kit, with removable strips.
Human
IHC, WB
$523
Cat # M03689
100 µl
Cat # M03689
100 µl
REN Overview
Facts about Renin.
Renin (REN)
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, sparking a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. .
Gene Information
| Human | |
|---|---|
| Gene Name: | REN |
| Uniprot: | P00797 |
| Entrez: | 5972 |
Family
| Belongs to: |
|---|
| peptidase A1 family |
Alternative Names
angiotensin-forming enzyme; Angiotensinogenase; EC 3.4.23; EC 3.4.23.15; FLJ10761; HNFJ2; REN; renin precursor, renal; Renin
Molecular Weight
Mass (kDA):
45.057 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q32.1 |
| Sequence: | 1; NC_000001.11 (204154819..204166337, complement) |
Subcellular Localizations
Secreted. Membrane. Associated to membranes via binding to ATP6AP2.
Diseases
- Hypertensive Disease
- Neoplasms
- Malignant Neoplasms
- Mesothelioma
- Malignant Paraganglionic Neoplasm
- Kidney Diseases
- Essential Hypertension
- Malignant Mesothelioma
- Cell Transformation, Neoplastic
- Pleural Neoplasms
- Hypertrophy
- Medulloblastoma
- Hemorrhage
Interacting Proteins
- AGT
Pathways
- Pathogenesis
- Localization
- Secretion
- Transport
- Cell Proliferation
- Excretion
- Cell Death
- Oncogenesis
- Glycosylation
- Ovulation
- Aging
- Translation
- Proprioception
PTMs
- Cleavage
- Phosphorylation
- Ubiquitination
- Glycosylation
- Deacetylation
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/REN
bosterbio.com/bosterbio-gene-info-cards/REN
References
PMID: 6324167 by Imai T., et al. Cloning and sequence analysis of cDNA for human renin precursor.
PMID: 3530608 by Morris B.J.; New possibilities for intracellular renin and inactive renin now that the structure of the human renin gene has been elucidated.