PROC Antibodies

AND PROC ELISA kits, PROC Proteins

Many biological assays use antibodies to detect PROC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PROC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PROC antibodies...

We validate the specificity of these antibodies to PROC by testing them on tissues known to express PROC positively and negatively. Browse below to find the PROC antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PROC Infographic by Boster Bio

All PROC Products

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Product

Figures

Specificity

Applications

Price

Anti-Protein C/PROC Antibody Picoband®

3 Q&As

Western blot analysis of Protein C using anti-Protein C antibody (PA1682)

IHC analysis of Protein C using anti-Protein C antibody (PA1682)

Flow Cytometry analysis of A549 cells using anti-PROC antibody (PA1682)

Human

Flow Cytometry, IHC, ICC, WB

$370
Cat # PA1682
100 μg/vial

Anti-Protein C/PROC Antibody Picoband®

Western blot analysis of Protein C using anti-Protein C antibody (A01742)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A01742
100 μg/vial

Human PROC/Protein C ELISA Kit PicoKine®

7 Q&As

Human

ELISA

$499
Cat # EK1975
96 wells/kit, with removable strips.

Protein C (PROC) (NM_000312) Human Recombinant Protein

Coomassie blue staining of purified PROC protein

$1062
Cat # PROTP04070
20 µg

Anti-Protein C Rabbit Monoclonal Antibody

Western blot analysis of Protein C expression in HepG2 cell lysate

Human

$370
Cat # M01742
100 μl/vial

Protein C (PROC) (NM_000312) Human Over-expression Lysate

Human

$628
Cat # LS005624
20 µg, 100 µg

PROC Overview

Facts about Vitamin K-dependent protein C.

PROC 3D structure. Source: alphafold

Vitamin K-dependent protein C (PROC)

Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids (PubMed:25618265). Exerts a protective effect on the endothelial cell barrier function (PubMed:25651845).

Gene Information

Human
Gene Name:	PROC
Uniprot:	P04070
Entrez:	5624

Family

Belongs to:

peptidase S1 family

Alternative Names

Anticoagulant protein C; APC; Autoprothrombin IIA; Blood coagulation factor XIV; Coagulation Factor XIV; EC 3.4.21; EC 3.4.21.69; PC; PROC; PROC1; protein C (inactivator of coagulation factors Va and VIIIa); Protein C; vitamin K-dependent protein C

Molecular Weight

Mass (kDA):
52.071 kDA

Genomic Context


Human

Location:	2q14.3
Sequence:	2; NC_000002.12 (127418143..127429246)

Tissue Specificity

Plasma; synthesized in the liver.

Subcellular Localizations

Secreted. Golgi apparatus. Endoplasmic reticulum.

Diseases

Salmonella Infections
Tuberculosis
Liver Diseases
Infective Disorder
Pain
Malignant Neoplasms
Neoplasms
Fracture
Congenital Heart Defects
Syphilis
Liver Dysfunction
Atherosclerosis
Staphylococcal Infections

Abscess
Chromosome Inversion
Cancer Patients And Suicide And Depression
Heart Diseases
Depressive Disorder
Stenosis
Cerebrovascular Accident

Interacting Proteins

MMP15

Pathways

Transport
Translation
Virulence
Mating
Secretion
Transposition
Urea Cycle
Fermentation
Coagulation
Pathogenesis
Cell Activation
Fertilization
Aging

Hypersensitivity
Sporulation
Reflex
Oligopeptide Transport
Antiport
Nitrogen Fixation
Cell Cycle

PTMs

Phosphorylation
Nitration
Oxidation

Reduction
Carbamylation
Glycosylation

Dephosphorylation

Research Areas

Apoptosis
Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PROC

References

PMID: 2991859 by Beckmann R.J., et al. The structure and evolution of a 461 amino acid human protein C precursor and its messenger RNA, based upon the DNA sequence of cloned human liver cDNAs.

PMID: 2991887 by Foster D.C., et al. The nucleotide sequence of the gene for human protein C.

10 Publications of Boster PROC Antibodies & ELISA Kits

PubMed ID: 22613815, Chen Aq, Liu Zw, Yang Zg, Leng Xj. Comp Biochem Physiol B Biochem Mol Biol. 2012...
PubMed ID: 20979618, Zhang S, He B, Goldstein S, Ge J, Wang Z, Ruiz G. Virol J. 2010 Oct 27;7:285. Do...
PubMed ID: 23054911, Zhang S, Zhang M, Goldstein S, Li Y, Ge J, He B, Ruiz G. Cell Biochem Biophys. 2...
PubMed ID: 24746831, Tang Y, Li Y, Yu H, Gao C, Liu L, Chen S, Xing M, Liu L, Yao P. J Nutr Biochem. ...
PubMed ID: 21486673, Bao Hj, Liu Y, Qin Jh, Xu Cs, Hei Nn, Jaber Jr, Chen Qs. Res Vet Sci. 2011 Dec;9...
PubMed ID: 24836450, Ban Jb, Fan Xw, Huang Q, Li Bf, Chen C, Zhang Hc, Xu Sq. Plos One. 2014 May 16;9...
PubMed ID: 21310960, Yang H, Gu J, Zheng Q, Li M, Lian X, Miao J, Jiang J, Wei W. J Biol Chem. 2011 A...
PubMed ID: 25311085, Li Jt, Wang Lf, Zhao Yl, Yang T, Li W, Zhao J, Yu F, Wang L, Meng Yl, Liu Nn, Zh...
PubMed ID: 26022197, Liu R, An L, Liu G, Li X, Tang W, Chen X. Antiviral Res. 2015 Aug;120:101-11. Do...
PubMed ID: 23331186, Aksu I, Baykara B, Kiray M, Gurpinar T, Sisman Ar, Ekerbicer N, Tas A, Gokdemir-...

*More publications can be found for each product on its corresponding product page